| | Normal | DCM | MSCs |
|---|
LVAWD (mm) | 2.359 ± 0.2079 | 1.270 ± 0.1633** | 1.461 ± 0.1429** |
LVAWS (mm) | 3.900 ± 0.3437 | 2.180 ± 0.2090** | 2.721 ± 0.2734**,# |
LVIDD (mm) | 6.682 ± 0.5339 | 8.206 ± 0.7136* | 8.088 ± 0.6103* |
LVIDS (mm) | 2.980 ± 0.5424 | 5.055 ± 0.8686* | 4.546 ± 0.5697* |
LVPWD (mm) | 2.462 ± 0.0453 | 1.316 ± 0.2192** | 1.531 ± 0.1489** |
LVPWS (mm) | 4.073 ± 0.0453 | 2.309 ± 0.3865** | 2.625 ± 0.2400* |
LVEF (%) | 85.043 ± 3.9506 | 66.729 ± 7.7492* | 72.898 ± 6.4846 |
FS (%) | 55.590 ± 4.5736 | 38.699 ± 6.2141* | 43.811 ± 5.8114* |
E’/A’ | 1.011 ± 0.0820 | 0.788 ± 0.1056* | 0.954 ± 0.1056# |
- Data are presented as the mean ± SEM, n = 3–6 per group. LVAWD, LVAWS, LVPWD, LVPWS, LVIDD and LVIDS reflect ventricular structure and were measured at the lateral papillary muscle along the short axis. LVEF and FS represent ventricular contractile function and were calculated by systolic and diastolic indexes. E’/A’ reflects ventricular diastolic function and was captured by measuring mitral annular velocity. LVAWD: left ventricular end-diastolic anterior wall thickness; LVAWS: left ventricular end-systolic anterior wall thickness; LVIDD: left ventricular end-diastolic internal diameter; LVIDS: left ventricular end-systolic internal diameter; LVPWD: left ventricular end-diastolic posterior wall thickness; LVPWS: left ventricular end-systolic posterior wall thickness; LVEF: left ventricular ejection fraction; FS: fractional shortening; E’/A’: the ratio of the early to the late peak diastolic velocity. *P < 0.05, **P < 0.01 vs. normal Control; #P < 0.05 vs. DCM
