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Table 1 Demographic and clinical characteristics of human subjects

From: Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes

 

Controls (n = 48)

T1DM (n = 29)

Age (years)

32.3 ± 1.4

32.5 ± 1.7

SBP (mmHg)

116.2 ± 1.8

136.0 ± 1.8*

DBP (mmHg)

73.2 ± 1.1

74.2 ± 1.3

Glucose (mg/dL)

87.7 ± 1.6

160.3 ± 13.6***

HbA1c (%)

5.3 ± 0.1

7.6 ± 0.2***

BMI

23.3 ± 0.6

25.5 ± 0.5

Total cholesterol (mg/dL)

182.2 ± 4.1

175.7 ± 5.4

HDL-C (mg/dL)

61.46 ± 1.7

56.8 ± 1.5

LDL-C (mg/dL)

116.12 ± 3.2

114.3 ± 4.5

apoB (mg/dL)

84.88 ± 2.7

84.77 ± 3.4

Triglycerides (mg/dL)

75.9 ± 4.3

67.7 ± 4.7

CC-IMT (mm)

0.41 ± 0.01

0.46 ± 0.01**

% of lipid-lowering therapies (statins)

0

19.35***

  1. SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, apoB apolipoprotein B, CC-IMT common carotid intima-media thickness
  2. * p < 0.05; ** p < 0.01; *** p < 0.001. Statistical significance was assessed by Mann–Whitney U test