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Table 1 Demographic and clinical characteristics of human subjects

From: Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes

  Controls (n = 48) T1DM (n = 29)
Age (years) 32.3 ± 1.4 32.5 ± 1.7
SBP (mmHg) 116.2 ± 1.8 136.0 ± 1.8*
DBP (mmHg) 73.2 ± 1.1 74.2 ± 1.3
Glucose (mg/dL) 87.7 ± 1.6 160.3 ± 13.6***
HbA1c (%) 5.3 ± 0.1 7.6 ± 0.2***
BMI 23.3 ± 0.6 25.5 ± 0.5
Total cholesterol (mg/dL) 182.2 ± 4.1 175.7 ± 5.4
HDL-C (mg/dL) 61.46 ± 1.7 56.8 ± 1.5
LDL-C (mg/dL) 116.12 ± 3.2 114.3 ± 4.5
apoB (mg/dL) 84.88 ± 2.7 84.77 ± 3.4
Triglycerides (mg/dL) 75.9 ± 4.3 67.7 ± 4.7
CC-IMT (mm) 0.41 ± 0.01 0.46 ± 0.01**
% of lipid-lowering therapies (statins) 0 19.35***
  1. SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, apoB apolipoprotein B, CC-IMT common carotid intima-media thickness
  2. * p < 0.05; ** p < 0.01; *** p < 0.001. Statistical significance was assessed by Mann–Whitney U test