Fig. 7From: Identification of novel inhibitors for TNFα, TNFR1 and TNFα-TNFR1 complex using pharmacophore-based approachesThe ADMET properties (2D structure of each ligand atoms, physicochemical filter positioning, compound complexity, oral property space, oral absorption estimation and Pfizer 3/75 rule positioning) of a the best TNF-α inhibitor (ZINC09609430), b the TNFR1 inhibitor (ZINC02968981), and c the TNF-α–TNFR1 complex inhibitor (ZINC05462670)Back to article page