Proteomic profiling of plasma biomarkers in acute ischemic stroke due to large vessel occlusion

Table 4 Correlation analysis of each biomarker with prognosis in AIS with different collaterals

Proteins	AIS with good collaterals (n = 17)	AIS with poor collaterals (n = 16)	P value	OR^a (95% CI^a)	P^a value	OR^b (95% CI^b)	P^b value
IGF2	1.35 ± 0.41	1.02 ± 0.35	0.022	0.115 (0.016–0.841)	0.033	0.115 (0.015–0.866)	0.036
LYVE1	1.82 ± 0.58	1.39 ± 0.42	0.026	0.183 (0.036–0.918)	0.039	0.028 (0.002–0.334)	0.005
PPBP	1.37 ± 0.73	1.81 ± 0.77	0.111	1.939 (0.707–5.321)	0.198	2.806 (0.933–8.439)	0.066
THBS1	0.72 ± 0.42	1.56 ± 1.02	0.005	4.257 (1.273–14.228)	0.019	3.294 (1.158–9.372)	0.025

Data are shown as mean ± SD
OR odds ratio, CI confidence interval, IGF2 insulin like growth factor 2, LYVE1 lymphatic vessel endothelial hyaluronan receptor 1, PPBP pro-platelet basic protein, THBS1 thrombospondin 1
^aLogistic regression analysis of each biomarker with different collaterals, OR and 95% CI with adjusting for age, gender, blood pressure, medical history and blood test
^bLogistic regression analysis each biomarker with prognosis, OR and 95% CI with adjusting for age, gender, blood pressure, medical history and blood test

ISSN: 1479-5876