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Table 2 miRNA transcripts displaying a significant differential expression in patients with CRC compared to control patients

From: EV-associated miRNAs from peritoneal lavage as potential diagnostic biomarkers in colorectal cancer

miRNA LogFC p-value Adj. p-value AUC AUC 95% CI_lower AUC 95% CI_upper Accuracy Sensitivity Specificity
hsa-miR-199b-5p_478486_mir − 12.82 2.59E−08 9.85E−07 1 1 1 0.967 0.968 0.964
hsa-miR-150-5p_477918_mir 2.58 7.10E−05 3.41E−04 0.978 0.959 0.996 0.919 0.936 0.899
hsa-miR-29c-5p_478005_mir − 2.93 2.78E−08 9.85E−07 0.973 0.954 0.991 0.943 0.943 0.944
hsa-miR-218-5p_477977_mir − 8.16 6.51E−07 8.25E−06 0.97 0.945 0.995 0.913 0.905 0.921
hsa-miR-99a-3p_479224_mir − 4.89 1.51E−08 8.95E−07 0.97 0.95 0.99 0.94 0.976 0.9
hsa-miR-383-5p_478079_mir − 8.33 3.55E−15 1.26E−12 0.968 0.952 0.985 0.939 0.94 0.938
hsa-miR-199a-3p_477961_mir − 6.16 2.84E−09 2.65E−07 0.968 0.942 0.994 0.905 0.92 0.887
hsa-miR-193a-5p_477954_mir − 3.62 1.32E−06 1.56E−05 0.962 0.932 0.991 0.873 0.852 0.897
hsa-miR-10b-5p_478494_mir − 2.79 2.58E−07 4.17E−06 0.957 0.93 0.983 0.871 0.875 0.866
hsa-miR-181c-5p_477934_mir − 3.52 1.23E−05 8.74E−05 0.952 0.929 0.974 0.833 0.859 0.803
hsa-miR-708-5p_478197_mir − 6.45 9.72E−08 2.29E−06 0.946 0.917 0.975 0.877 0.834 0.926
hsa-miR-125b-5p_477885_mir − 2.35 9.27E−07 1.13E−05 0.946 0.918 0.974 0.885 0.884 0.885
hsa-miR-140-5p_477909_mir − 5.82 4.59E−05 2.39E−04 0.943 0.919 0.968 0.817 0.825 0.807
hsa-miR-451a_478107_mir − 8.35 1.34E−07 2.64E−06 0.942 0.913 0.972 0.843 0.881 0.8
hsa-miR-148b-3p_477824_mir − 3.05 1.42E−07 2.66E−06 0.942 0.916 0.968 0.834 0.853 0.813
hsa-miR-130a-3p_477851_mir − 2.62 1.85E−06 2.00E−05 0.94 0.909 0.972 0.861 0.884 0.835
hsa-miR-214-3p_477974_mir − 7.59 1.19E−07 2.49E−06 0.937 0.901 0.972 0.896 0.94 0.846
hsa-miR-10a-5p_479241_mir − 2.19 1.44E−02 2.82E−02 0.937 0.906 0.969 0.897 0.904 0.889
hsa-miR-497-5p_478138_mir − 3.68 2.13E−04 8.08E−04 0.936 0.911 0.961 0.814 0.829 0.797
hsa-miR-143-3p_477912_mir − 3.15 1.58E−06 1.81E−05 0.936 0.906 0.965 0.86 0.868 0.85
hsa-miR-20a-5p_478586_mir − 2.79 5.14E−08 1.30E−06 0.933 0.901 0.964 0.877 0.906 0.843
hsa-miR-29c-3p_479229_mir − 3.55 2.14E−04 8.08E−04 0.931 0.897 0.965 0.86 0.84 0.883
hsa-miR-17-5p_478447_mir − 3.68 4.83E−05 2.41E−04 0.93 0.893 0.966 0.874 0.898 0.847
hsa-miR-486-5p_478128_mir − 11.10 2.21E−07 3.73E−06 0.929 0.899 0.958 0.853 0.818 0.893
hsa-miR-145-5p_477916_mir − 3.07 6.47E−06 5.34E−05 0.929 0.899 0.958 0.877 0.901 0.851
hsa-miR-214-5p_478768_mir − 8.13 2.33E−08 9.85E−07 0.923 0.885 0.96 0.877 0.906 0.844
hsa-miR-20b-5p_477804_mir − 11.65 3.73E−09 2.65E−07 0.921 0.887 0.956 0.883 0.879 0.887
hsa-miR-551b-3p_478159_mir − 9.71 2.07E−10 3.68E−08 0.919 0.885 0.953 0.852 0.906 0.79
hsa-miR-107_478254_mir − 4.70 1.35E−03 3.73E−03 0.917 0.883 0.951 0.919 0.938 0.898
hsa-miR-202-5p_478755_mir − 7.19 5.11E−08 1.30E−06 0.915 0.876 0.954 0.855 0.867 0.842
hsa-miR-93-5p_478210_mir − 2.84 3.88E−04 1.30E−03 0.915 0.875 0.954 0.86 0.872 0.847
hsa-miR-483-3p_478122_mir − 7.01 3.69E−09 2.65E−07 0.913 0.877 0.949 0.837 0.884 0.784
hsa-miR-652-3p_478189_mir − 2.05 2.63E−05 1.70E−04 0.913 0.882 0.945 0.825 0.831 0.818
hsa-miR-29b-3p_478369_mir − 3.59 3.71E−06 3.47E−05 0.911 0.877 0.945 0.836 0.834 0.838
hsa-miR-328-3p_478028_mir − 5.03 2.86E−04 1.01E−03 0.908 0.874 0.941 0.819 0.798 0.842
hsa-miR-25-3p_477994_mir − 2.37 3.44E−05 1.99E−04 0.908 0.87 0.946 0.865 0.899 0.827
hsa-miR-26a-5p_477995_mir − 2.30 1.99E−05 1.38E−04 0.904 0.872 0.937 0.796 0.799 0.791
hsa-miR-296-5p_477836_mir − 6.51 3.42E−05 1.99E−04 0.903 0.865 0.941 0.878 0.796 0.973
hsa-miR-144-3p_477913_mir − 5.05 3.53E−05 1.99E−04 0.903 0.867 0.938 0.827 0.85 0.801
hsa-miR-769-5p_478203_mir − 3.98 3.53E−05 1.99E−04 0.903 0.864 0.942 0.899 0.901 0.896
hsa-miR-181a-5p_477857_mir − 2.13 5.21E−06 4.52E−05 0.902 0.865 0.939 0.843 0.895 0.783
hsa-miR-29a-3p_478587_mir − 3.12 1.16E−03 3.38E−03 0.901 0.86 0.942 0.878 0.854 0.905
hsa-miR-152-3p_477921_mir − 3.98 2.17E−05 1.48E−04 0.9 0.866 0.934 0.804 0.791 0.819
hsa-miR-125b-1-3p_478665_mir − 9.13 1.93E−07 3.42E−06 0.895 0.86 0.931 0.86 0.868 0.851
hsa-miR-30a-3p_478273_mir − 1.66 9.38E−05 4.27E−04 0.891 0.854 0.928 0.812 0.793 0.834
hsa-miR-449b-5p_479528_mir − 10.10 2.30E−08 9.85E−07 0.889 0.846 0.932 0.88 0.908 0.847
hsa-miR-219a-5p_477980_mir − 6.58 5.10E−07 7.54E−06 0.889 0.852 0.926 0.84 0.854 0.824
hsa-miR-125a-5p_477884_mir − 1.40 1.48E−03 4.02E−03 0.888 0.846 0.93 0.827 0.84 0.813
hsa-miR-374b-3p_479421_mir − 4.64 2.15E−06 2.24E−05 0.887 0.845 0.929 0.8 0.791 0.81
hsa-miR-101-3p_477863_mir − 4.19 6.98E−05 3.39E−04 0.886 0.845 0.927 0.832 0.896 0.759
hsa-miR-452-5p_478109_mir − 3.88 2.89E−05 1.80E−04 0.886 0.852 0.92 0.751 0.737 0.766
hsa-miR-193a-3p_478306_mir − 2.46 2.37E−03 5.97E−03 0.884 0.841 0.928 0.869 0.899 0.835
hsa-miR-148a-3p_477814_mir − 1.48 1.24E−03 3.52E−03 0.884 0.845 0.923 0.822 0.818 0.826
hsa-miR-133a-3p_478511_mir − 6.89 1.67E−04 6.73E−04 0.883 0.843 0.922 0.827 0.853 0.797
hsa-miR-675-5p_478196_mir − 4.22 5.46E−06 4.61E−05 0.883 0.845 0.92 0.766 0.721 0.817
hsa-miR-34a-5p_478048_mir − 2.04 3.41E−05 1.99E−04 0.882 0.841 0.922 0.823 0.801 0.848
hsa-miR-582-5p_478166_mir − 8.33 3.37E−07 5.20E−06 0.881 0.842 0.92 0.84 0.767 0.923
hsa-miR-2110_477971_mir − 4.46 2.45E−06 2.48E−05 0.879 0.837 0.92 0.782 0.794 0.769
hsa-miR-185-5p_477939_mir − 2.69 1.09E−02 2.18E−02 0.879 0.836 0.921 0.828 0.872 0.777
hsa-miR-144-5p_477914_mir − 11.46 4.47E−08 1.30E−06 0.877 0.833 0.921 0.873 0.944 0.791
hsa-miR-199a-5p_478231_mir − 7.83 1.24E−04 5.31E−04 0.877 0.831 0.923 0.772 0.712 0.84
hsa-miR-361-5p_478056_mir − 1.48 9.56E−04 2.83E−03 0.877 0.837 0.918 0.821 0.86 0.778
hsa-miR-195-5p_477957_mir − 2.80 2.19E−04 8.17E−04 0.875 0.832 0.919 0.835 0.822 0.849
hsa-miR-136-5p_478307_mir − 8.01 5.88E−07 8.03E−06 0.873 0.834 0.913 0.828 0.821 0.836
hsa-miR-548d-5p_480870_mir − 3.80 3.79E−03 8.96E−03 0.873 0.827 0.919 0.755 0.65 0.875
hsa-miR-30b-5p_478007_mir − 2.55 2.64E−03 6.47E−03 0.873 0.829 0.916 0.774 0.795 0.751
hsa-miR-363-3p_478060_mir − 8.98 3.58E−05 1.99E−04 0.869 0.825 0.914 0.782 0.776 0.789
hsa-miR-27b-3p_478270_mir − 2.46 2.87E−02 4.90E−02 0.868 0.828 0.908 0.76 0.815 0.698
hsa-miR-24-3p_477992_mir − 2.06 4.68E−05 2.40E−04 0.868 0.823 0.913 0.859 0.9 0.813
hsa-miR-499a-5p_478139_mir − 4.05 4.42E−05 2.34E−04 0.864 0.821 0.908 0.851 0.875 0.824
hsa-miR-15a-5p_477858_mir − 1.96 3.80E−04 1.28E−03 0.863 0.823 0.903 0.77 0.781 0.758
hsa-miR-31-3p_478012_mir − 5.27 2.92E−04 1.02E−03 0.86 0.817 0.904 0.799 0.766 0.836
hsa-miR-18a-3p_477944_mir − 4.70 5.55E−05 2.74E−04 0.859 0.817 0.901 0.761 0.747 0.777
hsa-miR-92a-3p_477827_mir − 1.48 5.48E−04 1.74E−03 0.859 0.811 0.907 0.813 0.822 0.804
hsa-miR-130b-3p_477840_mir − 5.57 3.72E−04 1.27E−03 0.858 0.815 0.901 0.748 0.644 0.866
hsa-let-7b-5p_478576_mir − 1.57 5.76E−04 1.81E−03 0.858 0.814 0.902 0.76 0.758 0.761
hsa-miR-30e-3p_478388_mir − 4.70 5.51E−03 1.22E−02 0.854 0.81 0.899 0.753 0.628 0.897
hsa-miR-23b-5p_477991_mir − 3.62 3.36E−05 1.99E−04 0.853 0.81 0.896 0.756 0.758 0.754
hsa-miR-29b-2-5p_478003_mir − 4.33 2.79E−06 2.75E−05 0.85 0.806 0.894 0.797 0.806 0.786
hsa-miR-30e-5p_479235_mir − 8.36 6.16E−04 1.92E−03 0.849 0.802 0.896 0.709 0.638 0.791
hsa-miR-200c-3p_478351_mir − 7.14 2.32E−05 1.53E−04 0.848 0.802 0.894 0.802 0.721 0.894
hsa-miR-1180-3p_477869_mir − 3.91 4.43E−05 2.34E−04 0.847 0.798 0.896 0.806 0.754 0.866
hsa-miR-190a-5p_478358_mir − 1.89 1.87E−02 3.48E−02 0.847 0.801 0.892 0.829 0.814 0.847
hsa-miR-151b_477811_mir − 9.82 2.25E−04 8.31E−04 0.846 0.801 0.892 0.761 0.733 0.792
hsa-miR-505-5p_478957_mir − 5.86 4.24E−05 2.32E−04 0.846 0.801 0.891 0.796 0.805 0.786
hsa-miR-196b-5p_478585_mir − 6.46 1.86E−06 2.00E−05 0.845 0.795 0.894 0.767 0.67 0.879
hsa-miR-324-5p_478024_mir − 1.51 8.13E−03 1.65E−02 0.843 0.797 0.889 0.777 0.754 0.802
hsa-miR-224-5p_477986_mir − 2.72 1.58E−04 6.45E−04 0.842 0.8 0.883 0.746 0.695 0.804
hsa-miR-139-5p_478312_mir − 5.12 2.43E−04 8.80E−04 0.839 0.794 0.885 0.727 0.725 0.729
hsa-miR-545-5p_479003_mir − 5.30 8.42E−06 6.79E−05 0.838 0.79 0.886 0.79 0.79 0.79
hsa-miR-222-3p_477982_mir − 2.08 7.82E−04 2.37E−03 0.838 0.791 0.884 0.728 0.762 0.689
hsa-miR-340-5p_478042_mir − 9.05 9.31E−06 7.18E−05 0.836 0.79 0.882 0.803 0.817 0.786
hsa-miR-504-5p_478144_mir − 3.54 1.86E−04 7.18E−04 0.836 0.787 0.886 0.778 0.729 0.833
hsa-miR-106a-5p_478225_mir − 10.76 4.30E−08 1.30E−06 0.834 0.784 0.883 0.816 0.924 0.693
hsa-miR-1271-5p_478674_mir − 9.10 3.87E−06 3.52E−05 0.834 0.785 0.883 0.823 0.9 0.734
hsa-miR-125b-2-3p_478666_mir − 6.80 9.11E−06 7.18E−05 0.834 0.782 0.886 0.804 0.866 0.735
hsa-miR-339-3p_478325_mir − 3.60 6.56E−03 1.39E−02 0.834 0.782 0.886 0.778 0.692 0.876
hsa-miR-483-5p_478432_mir − 6.45 5.42E−07 7.69E−06 0.832 0.783 0.882 0.785 0.871 0.687
hsa-miR-584-5p_478167_mir − 10.36 6.40E−07 8.25E−06 0.831 0.781 0.882 0.803 0.906 0.685
hsa-miR-17-3p_477932_mir − 8.43 2.22E−05 1.49E−04 0.831 0.779 0.883 0.805 0.861 0.741
hsa-miR-570-3p_479053_mir − 4.46 1.11E−04 4.79E−04 0.831 0.785 0.876 0.766 0.697 0.844
hsa-miR-625-5p_479469_mir − 10.93 4.36E−06 3.87E−05 0.83 0.781 0.88 0.806 0.865 0.738
hsa-miR-196a-5p_478230_mir − 7.37 1.01E−05 7.64E−05 0.83 0.777 0.883 0.812 0.879 0.735
hsa-miR-7-1-3p_478198_mir − 7.37 1.00E−04 4.52E−04 0.829 0.783 0.874 0.762 0.646 0.895
hsa-miR-450b-5p_478914_mir − 9.65 1.03E−07 2.29E−06 0.828 0.775 0.88 0.803 0.906 0.685
hsa-miR-221-5p_478778_mir − 5.01 3.08E−04 1.06E−03 0.827 0.779 0.875 0.745 0.64 0.865
hsa-miR-128-3p_477892_mir − 1.32 5.21E−03 1.16E−02 0.823 0.772 0.874 0.743 0.741 0.746
hsa-miR-491-5p_478132_mir − 3.50 1.88E−03 4.92E−03 0.822 0.774 0.87 0.743 0.703 0.79
hsa-miR-136-3p_477902_mir − 7.94 2.78E−05 1.76E−04 0.821 0.771 0.871 0.786 0.855 0.707
hsa-miR-101-5p_478620_mir − 7.44 1.09E−05 8.08E−05 0.819 0.766 0.873 0.812 0.877 0.738
hsa-miR-151a-3p_477919_mir − 1.93 2.85E−04 1.01E−03 0.819 0.769 0.87 0.803 0.854 0.745
hsa-miR-28-3p_477999_mir − 2.25 4.30E−03 1.00E−02 0.817 0.771 0.863 0.738 0.728 0.749
hsa-miR-489-3p_478130_mir − 4.40 1.33E−04 5.62E−04 0.815 0.766 0.865 0.76 0.736 0.787
hsa-miR-106b-3p_477866_mir − 2.41 6.48E−03 1.39E−02 0.815 0.765 0.866 0.72 0.693 0.751
hsa-miR-324-3p_478023_mir − 7.87 2.85E−04 1.01E−03 0.814 0.766 0.861 0.761 0.686 0.847
hsa-miR-125a-3p_477883_mir − 3.24 4.18E−04 1.39E−03 0.811 0.76 0.862 0.765 0.741 0.791
hsa-let-7i-3p_477862_mir − 6.66 4.69E−04 1.54E−03 0.81 0.759 0.861 0.747 0.665 0.841
hsa-miR-33b-5p_478479_mir − 5.49 2.06E−03 5.30E−03 0.81 0.758 0.862 0.704 0.626 0.793
hsa-miR-503-5p_478143_mir − 2.80 6.04E−03 1.31E−02 0.81 0.757 0.863 0.762 0.726 0.805
hsa-miR-301a-3p_477815_mir − 5.08 1.51E−03 4.05E−03 0.809 0.76 0.858 0.723 0.608 0.856
hsa-miR-330-3p_478030_mir − 5.72 7.79E−04 2.37E−03 0.805 0.754 0.856 0.761 0.645 0.892
hsa-miR-425-5p_478094_mir − 1.51 2.66E−02 4.63E−02 0.805 0.757 0.852 0.728 0.714 0.744
hsa-miR-16-2-3p_477931_mir − 3.32 1.12E−02 2.22E−02 0.804 0.747 0.862 0.78 0.769 0.793
hsa-miR-548k_479374_mir − 14.17 8.73E−03 1.76E−02 0.801 0.757 0.845 0.718 0.654 0.79
hsa-miR-429_477849_mir − 2.00 1.76E−02 3.37E−02 0.801 0.747 0.854 0.768 0.807 0.723
hsa-miR-598-3p_478172_mir − 1.51 4.51E−03 1.04E−02 0.8 0.754 0.847 0.696 0.726 0.661
hsa-miR-887-3p_479189_mir − 5.41 1.42E−04 5.95E−04 0.799 0.748 0.85 0.737 0.632 0.858
hsa-miR-93-3p_478209_mir − 4.60 2.28E−04 8.33E−04 0.798 0.745 0.852 0.749 0.702 0.801
hsa-miR-629-5p_478183_mir − 6.16 1.75E−04 6.90E−04 0.796 0.746 0.846 0.753 0.678 0.839
hsa-miR-21-5p_477975_mir 1.32 7.91E−03 1.61E−02 0.796 0.751 0.842 0.683 0.688 0.677
hsa-miR-140-3p_477908_mir − 3.42 6.10E−03 1.31E−02 0.793 0.743 0.843 0.734 0.752 0.713
hsa-miR-425-3p_478093_mir − 5.28 9.90E−04 2.90E−03 0.792 0.74 0.844 0.728 0.588 0.888
hsa-miR-200a-5p_478752_mir 3.05 2.34E−02 4.15E−02 0.792 0.735 0.85 0.713 0.693 0.736
hsa-miR-590-3p_478168_mir − 4.77 1.27E−03 3.56E−03 0.791 0.739 0.842 0.702 0.637 0.776
hsa-miR-30a-5p_479448_mir − 8.52 7.71E−04 2.37E−03 0.789 0.738 0.841 0.734 0.726 0.744
hsa-let-7 g-3p_477850_mir − 6.38 1.74E−04 6.90E−04 0.787 0.733 0.84 0.756 0.608 0.926
hsa-miR-542-3p_478153_mir − 8.15 2.88E−06 2.76E−05 0.786 0.729 0.842 0.778 0.901 0.638
hsa-miR-31-5p_478015_mir − 1.78 7.34E−03 1.51E−02 0.786 0.737 0.835 0.676 0.708 0.64
hsa-miR-379-5p_478077_mir − 5.15 5.46E−04 1.74E−03 0.78 0.724 0.835 0.755 0.773 0.734
hsa-miR-194-5p_477956_mir − 1.66 1.21E−03 3.48E−03 0.78 0.724 0.836 0.778 0.861 0.683
hsa-miR-34c-5p_478052_mir − 2.51 4.47E−03 1.04E−02 0.779 0.726 0.832 0.685 0.639 0.738
hsa-miR-576-5p_478165_mir − 6.85 8.70E−05 4.01E−04 0.778 0.721 0.836 0.774 0.853 0.684
hsa-miR-28-5p_478000_mir − 5.87 1.45E−03 3.96E−03 0.778 0.726 0.829 0.731 0.64 0.835
hsa-miR-708-3p_479162_mir − 2.77 2.27E−03 5.75E−03 0.772 0.715 0.828 0.738 0.74 0.736
hsa-miR-505-3p_478145_mir − 2.12 3.62E−03 8.67E−03 0.771 0.718 0.824 0.758 0.737 0.781
hsa-miR-26b-5p_478418_mir − 1.01 2.37E−02 4.19E−02 0.768 0.717 0.819 0.692 0.714 0.666
hsa-miR-365a-3p_478065_mir − 4.75 2.67E−02 4.63E−02 0.767 0.713 0.822 0.661 0.495 0.85
hsa-miR-423-3p_478327_mir − 1.63 1.58E−03 4.19E−03 0.765 0.716 0.815 0.65 0.687 0.607
hsa-miR-338-5p_478038_mir − 3.61 2.40E−03 6.01E−03 0.761 0.703 0.819 0.704 0.719 0.687
hsa-miR-210-3p_477970_mir − 1.17 1.67E−02 3.22E−02 0.761 0.708 0.815 0.672 0.698 0.643
hsa-miR-551a_478158_mir − 5.58 1.97E−03 5.10E−03 0.76 0.699 0.822 0.741 0.69 0.8
hsa-miR-889-3p_478208_mir − 8.68 1.14E−05 8.28E−05 0.759 0.698 0.82 0.789 0.922 0.637
hsa-miR-301b-3p_477825_mir − 5.75 1.87E−02 3.48E−02 0.758 0.7 0.816 0.751 0.851 0.637
hsa-miR-590-5p_478367_mir − 3.83 1.63E−02 3.15E−02 0.757 0.703 0.812 0.707 0.59 0.841
hsa-miR-548am-5p_480872_mir − 3.25 1.13E−02 2.22E−02 0.757 0.703 0.81 0.663 0.526 0.82
hsa-miR-187-3p_477941_mir − 4.47 6.97E−03 1.46E−02 0.754 0.701 0.807 0.704 0.644 0.772
hsa-miR-450a-5p_478106_mir − 7.12 1.26E−03 3.56E−03 0.753 0.692 0.814 0.743 0.646 0.853
hsa-miR-376a-5p_478859_mir − 5.94 1.04E−04 4.56E−04 0.75 0.688 0.811 0.738 0.832 0.631
hsa-miR-1296-5p_479451_mir − 4.26 2.49E−03 6.17E−03 0.75 0.695 0.806 0.703 0.719 0.686
hsa-miR-181c-3p_477933_mir − 3.64 9.29E−04 2.77E−03 0.748 0.685 0.811 0.715 0.805 0.613
hsa-miR-1247-5p_477882_mir − 3.36 2.43E−02 4.26E−02 0.748 0.692 0.804 0.698 0.586 0.827
hsa-miR-34a-3p_478047_mir − 2.32 1.77E−02 3.37E−02 0.748 0.694 0.803 0.658 0.727 0.579
hsa-miR-654-3p_479135_mir − 7.56 4.77E−04 1.55E−03 0.74 0.681 0.799 0.76 0.692 0.839
hsa-miR-411-5p_478086_mir − 5.12 7.16E−03 1.49E−02 0.738 0.68 0.796 0.715 0.647 0.793
hsa-miR-181d-5p_479517_mir − 5.67 4.10E−03 9.63E−03 0.733 0.675 0.791 0.686 0.554 0.838
hsa-miR-200b-3p_477963_mir − 3.43 7.26E−03 1.50E−02 0.733 0.674 0.792 0.683 0.609 0.767
hsa-miR-299-3p_478792_mir − 6.51 4.73E−05 2.40E−04 0.732 0.67 0.794 0.748 0.893 0.582
hsa-miR-182-5p_477935_mir − 8.68 8.37E−05 3.91E−04 0.73 0.666 0.795 0.753 0.9 0.585
hsa-miR-410-3p_478085_mir − 5.65 1.22E−03 3.48E−03 0.728 0.67 0.787 0.753 0.771 0.733
hsa-miR-744-5p_478200_mir − 3.55 1.81E−02 3.40E−02 0.725 0.67 0.781 0.657 0.637 0.68
hsa-miR-96-5p_478215_mir − 6.84 1.03E−04 4.56E−04 0.724 0.658 0.79 0.744 0.886 0.583
hsa-miR-133b_480871_mir − 3.18 1.98E−02 3.66E−02 0.724 0.664 0.783 0.686 0.651 0.726
hsa-miR-544a_478156_mir − 5.67 1.37E−03 3.77E−03 0.719 0.66 0.779 0.756 0.81 0.694
hsa-miR-497-3p_478946_mir − 6.92 1.44E−04 5.95E−04 0.718 0.652 0.784 0.753 0.899 0.585
hsa-miR-331-3p_478323_mir − 5.93 3.27E−03 7.90E−03 0.715 0.656 0.774 0.761 0.775 0.744
hsa-let-7f-2-3p_477843_mir − 3.26 1.19E−02 2.33E−02 0.715 0.655 0.776 0.682 0.567 0.814
hsa-miR-195-3p_478744_mir − 4.54 6.67E−03 1.40E−02 0.712 0.652 0.773 0.717 0.712 0.723
hsa-miR-378a-5p_478076_mir − 5.30 2.12E−03 5.41E−03 0.71 0.65 0.769 0.723 0.584 0.882
hsa-miR-1-3p_477820_mir − 6.27 6.10E−03 1.31E−02 0.706 0.644 0.768 0.732 0.778 0.679
hsa-miR-615-3p_478175_mir − 3.14 4.99E−03 1.13E−02 0.706 0.643 0.769 0.696 0.652 0.746
hsa-miR-545-3p_479002_mir − 2.99 1.99E−02 3.66E−02 0.704 0.64 0.767 0.675 0.678 0.672
hsa-miR-548a-3p_478157_mir − 3.75 4.83E−03 1.10E−02 0.703 0.641 0.765 0.716 0.572 0.881
hsa-miR-1248_478653_mir − 2.64 1.08E−02 2.17E−02 0.702 0.642 0.763 0.707 0.764 0.643
hsa-miR-381-3p_477816_mir − 5.10 5.97E−03 1.31E−02 0.701 0.639 0.763 0.734 0.727 0.742
hsa-miR-627-5p_478427_mir − 4.94 5.01E−04 1.62E−03 0.701 0.632 0.77 0.735 0.863 0.589
hsa-miR-1301-3p_477897_mir − 5.30 5.52E−03 1.22E−02 0.696 0.638 0.754 0.711 0.596 0.843
hsa-miR-486-3p_478422_mir − 6.30 1.86E−04 7.18E−04 0.692 0.626 0.758 0.725 0.891 0.535
hsa-miR-200a-3p_478490_mir − 4.37 1.79E−02 3.39E−02 0.691 0.626 0.756 0.719 0.792 0.635
hsa-miR-15a-3p_477928_mir − 3.53 6.65E−03 1.40E−02 0.688 0.62 0.755 0.703 0.808 0.584
hsa-miR-548 g-3p_479020_mir − 2.12 2.25E−02 4.04E−02 0.687 0.625 0.75 0.691 0.759 0.613
hsa-miR-432-5p_478101_mir − 3.66 2.70E−02 4.65E−02 0.683 0.621 0.746 0.691 0.724 0.652
hsa-miR-15b-5p_478313_mir − 6.53 2.89E−02 4.90E−02 0.682 0.619 0.745 0.666 0.692 0.637
hsa-miR-132-5p_478705_mir − 6.01 3.23E−03 7.86E−03 0.68 0.614 0.745 0.734 0.867 0.582
hsa-let-7e-5p_478579_mir − 5.40 2.04E−02 3.72E−02 0.679 0.614 0.744 0.655 0.556 0.769
hsa-miR-485-5p_478126_mir − 2.09 2.46E−02 4.30E−02 0.678 0.613 0.743 0.688 0.734 0.634
hsa-miR-299-5p_478793_mir − 5.05 8.70E−04 2.62E−03 0.672 0.603 0.741 0.702 0.858 0.524
hsa-miR-16-1-3p_478727_mir − 4.44 1.55E−03 4.13E−03 0.669 0.603 0.735 0.699 0.841 0.537
hsa-miR-215-5p_478516_mir − 7.23 8.19E−05 3.88E−04 0.668 0.601 0.735 0.718 0.896 0.514
hsa-miR-103a-2-5p_477864_mir − 4.32 2.05E−02 3.73E−02 0.664 0.603 0.724 0.664 0.529 0.818
hsa-miR-29a-5p_478002_mir − 6.48 2.54E−03 6.26E−03 0.643 0.568 0.717 0.723 0.896 0.524
hsa-miR-874-3p_478205_mir − 2.80 2.77E−02 4.74E−02 0.638 0.575 0.701 0.617 0.524 0.722
hsa-miR-502-5p_478954_mir − 4.03 2.18E−02 3.93E−02 0.637 0.573 0.701 0.662 0.53 0.813
hsa-miR-542-5p_478337_mir − 5.28 3.71E−03 8.83E−03 0.633 0.564 0.702 0.68 0.855 0.481
hsa-miR-362-3p_478058_mir − 5.81 1.73E−03 4.56E−03 0.632 0.564 0.701 0.69 0.879 0.475
hsa-miR-431-3p_478888_mir − 4.55 4.63E−03 1.06E−02 0.624 0.552 0.696 0.678 0.853 0.478
hsa-miR-192-3p_478741_mir − 4.08 5.15E−03 1.16E−02 0.61 0.535 0.685 0.674 0.85 0.474
hsa-miR-589-5p_479073_mir − 2.81 2.28E−02 4.07E−02 0.582 0.512 0.652 0.633 0.795 0.448
hsa-miR-888-5p_479192_mir − 3.79 2.06E−02 3.73E−02 0.559 0.489 0.63 0.656 0.861 0.422
hsa-miR-15b-3p_477929_mir − 3.73 1.76E−02 3.37E−02 0.529 0.459 0.599 0.629 0.86 0.365
hsa-miR-651-5p_479131_mir − 3.94 2.90E−02 4.90E−02 0.523 0.448 0.599 0.638 0.87 0.372
  1. Log fold-change expression, p-value, adjusted p-value, AUC values, accuracy, sensitivity, specificity, and 95% of confidence intervals of the 210 dysregulated miRNAs
  2. CI confidence of interval