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Table 1 Demographic and clinical characteristics of colon carcinoma patients

From: Novel nomograms to predict lymph node metastasis and liver metastasis in patients with early colon carcinoma

Clinicopathological variables SEER cohort (n = 32,819) P value
  Entire cohort Training n = 21,880 Validation n = 10,939
Age 67.08 (13.40) 67.02 (13.38) 67.19 (13.42) 0.826
Gender
 Female 16,479 10,967 5512 0.659
 Male 16,340 10,913 5427  
Marital status
 Married 18,093 12,046 6047 0.922
 Single 12,668 8462 4206  
 Unknown 2058 1372 686  
Race
 American Indian/Alaska Native 223 154 69 0.735
 Asian or Pacific Islander 2467 1650 817  
 Black 3956 2658 1298  
 White 26,173 17,418 8755  
Histological grade
 Well differentiated 6214 4158 2056 0.172
 Moderately differentiated 23,529 15,634 7895  
 Poorly differentiated 2615 1761 854  
 Undifferentiated 461 327 134  
Histological type
 Adenocarcinoma 28,356 18,917 9439 0.620
 Carcinoid tumor 986 644 342  
 Neuroendocrine carcinoma 291 194 97  
 Mucinous adenocarcinoma 1585 1075 510  
 Other 1601 1050 551  
TNM
 I 27,708 18,482 9226 0.408
 II 91 58 33  
 III 4398 2906 1492  
 IV 619 431 188  
T classification
 T1 17,017 11,344 5673 0.990
 T2 15,802 10,536 5266  
N classification
 N0 28,114 18,769 9345 0.277
 N1 3971 2623 1348  
 N2 734 488 246  
M classification
 M0 32,200 21,449 10,751 0.512
 M1 619 431 188  
Tumor size
 < 5 cm 24,488 16,294 8194 0.536
 ≥ 5 cm 3565 2411 1154  
 Unknown 4766 3175 1591  
Liver metastasis
 Negative 32,364 21,557 10,807 0.06
 Positive 455 323 132  
Lung metastasis
 Negative 32,713 21,801 10,912 0.09
 Positive 91 67 24  
 Unknown 14 12 2  
Bone metastasis
 Negative 32,793 21,861 10,932 0.227
 Positive 14 12 2  
 Unknown 11 7 4  
Brain metastasis
 Negative 32,798 21,867 10,931 0.440
 Positive 5 4 1  
 Unknown 15 9 6  
CEA
 Negative 12,156 8111 4045 0.943
 Borderline 80 54 26  
 Positive 3385 2270 1115  
 Unknown 17,198 11,445 5753  
Tumor number
 1 22,789 15,214 7575 0.898
 2 7495 4989 2506  
 3 1914 1262 652  
 > 3 621 415 206  
Overall survival
 Alive 28,206 18,797 9409 0.812
 Dead 4613 3083 1530  
  1. CEA, carcinoembryonic antigen