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Table 1 Clinicopathologic characteristics of the total 598 gastric cancer patients

From: Regulatory T cells and M2 macrophages present diverse prognostic value in gastric cancer patients with different clinicopathologic characteristics and chemotherapy strategies

  n T cells M2 macrophages Tumor cells
FOXP3 CD3 CD8 CD163 PD-L1
Low (%) High (%) p value Low (%) High (%) p-value Low (%) High (%) p-value Low (%) High (%) p-value Neg (%) Pos (%) p-value
Gender 598    0.285    0.858    0.285    0.373    0.43
 Female 180 53.3 46.7   50.6 49.4   46.7 53.3   57.8 47.2   71.7 28.3  
 Male 418 48.6 51.4   49.8 50.2   51.4 48.6   48.8 51.2   68.4 31.6  
Age 598    0.024    0.019    0.676    0.08    0.204
 ≤ 60 239 55.6 44.4   43.9 56.1   49 51   54.4 45.6   66.1 33.9  
 > 60 359 46.2 53.8   53.8 46.2   50.7 49.3   47.1 52.9   71.6 28.4  
Location 598    0.334    0.473    0.321    0.186    0.977
 U 124 55.6 44.4   54.8 45.2   53.2 46.8   53.2 46.8   70.2 29.8  
 M 197 49.7 50.3   49.2 50.8   45.7 54.3   44.7 55.3   69 31  
 L 277 47.7 52.3   48.4 51.6   51.6 48.4   52.3 47.7   69.3 30.7  
Pathological classification 598    < 0.001    < 0.001    < 0.001    0.004    < 0.001
 Pap 14 28.6 71.4   85.7 14.3   92.9 7.1   50 50   64.3 35.7  
 Tub 183 49.2 50.8   54.1 45.9   53.6 46.4   51.9 48.1   51.4 48.6  
 Por 316 48.4 51.6   42.7 57.3   44.6 55.4   43.7 56.3   78.8 21.2  
 Sig & Muc 85 61.2 38.8   62.4 37.6   55.3 44.7   68.2 31.8   75.3 24.7  
T stage 598    0.097    0.044    0.002    0.632    < 0.001
 1 68 52.9 47.1   51.5 48.5   57.4 42.6   51.5 48.5   48.5 51.5  
 2 84 52.4 47.6   41.7 58.3   45.2 54.8   45.2 54.8   58.3 41.7  
 3 141 57.4 42.6   43.3 56.7   37.6 62.4   47.5 52.5   66 34  
 4 35 45.2 54.8   55.1 44.9   55 45   52.1 47.9   78.7 21.3  
N stage 598    0.176    0.499    0.398    0.612    < 0.001
 N0 224 46.4 53.6   48.2 51.8   47.8 52.2   51.3 48.7   53.6 46.4  
 N+ 374 52.1 47.9   51.1 48.9   51.3 48.7   49.2 50.8   78.9 21.1  
M stage 598    < 0.001    0.013    < 0.001    0.001    0.002
 M0 524 55.7 44.3   48.1 51.9   46.6 53.4   52.7 47.3   67.2 32.8  
 M+ 74 9.5 90.5   63.5 36.5   74.3 25.7   31.1 68.9   85.1 14.9  
pTNM 598    < 0.001    0.082    < 0.001    0.001    < 0.001
 1 108 49.1 50.9   47.2 52.8   54.7 45.3   51 49   47.3 52.7  
 2 150 57.3 42.7   46 54   40 60   58 42   50.7 49.3  
 3 266 57.5 42.5   49.6 50.4   47 53   54.5 45.5   80.5 19.5  
 4 74 9.5 90.5   63.5 36.5   74.3 25.7   31.1 68.9   85.1 14.9  
  1. U: upper parts; M: middle parts; L: lower parts; N0: no lymph node metastasis; N+: lymph node metastasis; Pap: papillary adenocarcinoma; Tub: tubular adenocarcinoma; Por: poor-differentiated adenocarcinoma; Sig: signet ring cell adenocarcinoma; Muc: mucinous adenocarcinoma; Neg: Negative; Pos: Postive