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Table 7 Uni- and multivariable analyses of multiple prognostic gene expression biomarkers in cytogenetically intermediate-risk AML

From: High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

Prognostic markers Univariable Multivariable
RFS OS RFS OS
p value p value p value HR (95% CI) p value HR (95% CI)
BAALC high vs. low 0.070 0.927     
CDKN1B high vs. low 0.229 0.583     
ERG high vs. low 0.009 0.001    0.008 5.541 (1.566–19.602)
MECOM/EVI1 high vs. low 0.513 0.409     
FLT3 high vs. low 0.001 0.006 0.008 3.314 (1.372–8.008)   
ID1 high vs. low 0.308 0.216     
IL2RA high vs. low < 0.001 0.004 < 0.001 8.171 (2.750–24.279) 0.044 2.765 (1.028–7.437)
MN1 high vs. low 0.847 0.211     
WT1 high vs. low 0.002 0.006     
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