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Table 7 Uni- and multivariable analyses of multiple prognostic gene expression biomarkers in cytogenetically intermediate-risk AML

From: High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

Prognostic markers

Univariable

Multivariable

RFS

OS

RFS

OS

p value

p value

p value

HR (95% CI)

p value

HR (95% CI)

BAALC high vs. low

0.070

0.927

    

CDKN1B high vs. low

0.229

0.583

    

ERG high vs. low

0.009

0.001

  

0.008

5.541 (1.566–19.602)

MECOM/EVI1 high vs. low

0.513

0.409

    

FLT3 high vs. low

0.001

0.006

0.008

3.314 (1.372–8.008)

  

ID1 high vs. low

0.308

0.216

    

IL2RA high vs. low

< 0.001

0.004

< 0.001

8.171 (2.750–24.279)

0.044

2.765 (1.028–7.437)

MN1 high vs. low

0.847

0.211

    

WT1 high vs. low

0.002

0.006

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