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Table 6 Uni and multivariable analyses on RFS and OS in intermediate-risk AML

From: High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

Variable Univariable Multivariable
RFS OS RFS OS
p value p value p value HR (95% CI) p value HR (95% CI)
Age group 0.633 0.223     
High WBC counts 0.512 0.300     
High blast percentage 0.759 0.779     
Secondary AML 0.705 0.168     
High IL2RA mRNA level < 0.001 < 0.001 < 0.001 6.637 (3.424–12.865) < 0.001 5.211 (2.129–12.752)
FLT3-ITD+ 0.006 0.006     
CEBPADM+ 0.930 0.071     
NPM1+ 0.685 0.898     
NPM1+FLT3-ITD 0.440 0.478