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Table 6 Uni and multivariable analyses on RFS and OS in intermediate-risk AML

From: High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

Variable

Univariable

Multivariable

RFS

OS

RFS

OS

p value

p value

p value

HR (95% CI)

p value

HR (95% CI)

Age group

0.633

0.223

    

High WBC counts

0.512

0.300

    

High blast percentage

0.759

0.779

    

Secondary AML

0.705

0.168

    

High IL2RA mRNA level

< 0.001

< 0.001

< 0.001

6.637 (3.424–12.865)

< 0.001

5.211 (2.129–12.752)

FLT3-ITD+

0.006

0.006

    

CEBPADM+

0.930

0.071

    

NPM1+

0.685

0.898

    

NPM1+FLT3-ITD−

0.440

0.478

    
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Journal of Translational Medicine

ISSN: 1479-5876

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