Fig. 6

CsA can abolish the combined inhibitory effect of AIBP and APOA-I. a Representative images and statistical analyses of tumors in mice inoculated with HCT116 cells co-expressing AIBP and APOA-I upon intraperitoneal administration of CsA (10 mg/kg). b The average radiant efficiency [(p/s/cm²/sr)/(μW/cm²)] of the tumors in mice (mean ± SD, n = 5, *P < 0.05; **P < 0.01). c The tumor microvessels were stained for CD31. d Vessel density (mm², mean ± SD, n = 5, *P < 0.05; **P < 0.01). e Representative images of migration and invasion of the indicated cells treated with or without CsA for 48 h (10 µM). f The corresponding cell number per frame was counted. Scale bar, 50 μm (mean ± SD, n = 10; **P < 0.01)