Fig. 8

Prognostic significance of the macrophage-related gene signature in the stratified cohorts. a–d Prognostic significance of the macrophage-related gene signature in different cohorts stratified by age (age ≤ 60 or age > 60, panels A and B, respectively) or grade (low grade and high grade, panels C and D, respectively). e–h The macrophage-related gene signature retained prognostic significance for glioma patients treated with or without pharmaceutical therapy (e and f) and radiotherapy (g and h). Optimal cutoff values were used to determine high- and low-risk groups in each stratified cohort, and the statistical significance of the difference between two K–M survival curves was assessed using the log-rank test