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TableĀ 2 Patients presenting with concomitant and multiple mutations in the KRAS, NRAS, BRAF and/or PIK3CA genes

From: Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer

Patient ID Gene aa substitution AF
K22-13 KRAS G12S 0.11
KRAS G12V 0.1
PIK3CA D725N 0.08
PIK3CA H1047Y 0.16
K26-13 KRAS G12D 0.39
KRAS T58I 0.08
BRAF S467L 0.12
K60-14 KRAS G12C 0.1
KRAS G13C 0.11
KRAS G12V 0.12
K13-14 KRAS G12D 0.31
KRAS V9F 0.09
BRAF R603L 0.16
K41-14 KRAS A59E 0.27
KRAS G12S 0.08
NRAS G12V 0.07
K65-13 KRAS A146V 0.44
BRAF G466V 0.33
K168-13 KRAS G12V 0.47
KRAS G15S 0.07
K35-13 KRAS G12C 0.06
KRAS G13D 0.54
K197-13 KRAS G13V 0.46
NRAS G13S 0.06
K10-14 KRAS G12D 0.06
BRAF G466V 0.11
K176-13 BRAF S467L 0.09
BRAF V600M 0.09
  1. aa, amino acid; AF, allelic frequency