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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production

Fig. 2

Schema illustrating procedural steps to generate therapeutic MSC doses. Pre-quantum expansion passage 1 (PreQE-P1) cells from Pigs 1 and 3 were seeded onto Quantum bioreactor. A single quantum run then yielded the cell bank quantum expansion 1 (QE-1) from which additional noncommittal quantum expansions generated the therapeutic doses termed as quantum expansion 2 (QE-2). During quantum expansion, cells were tested for metabolic activity and cells from QE-2 were then tested in in vitro assays of marker expression, differentiation and potency

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