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Table 1 Univariate and multivariate models for overall survival and progression-free survival in 132 gastric cancer patients who underwent chemotherapy in The Cancer Genome Atlas (TCGA)

From: Somatic mutation of DNAH genes implicated higher chemotherapy response rate in gastric adenocarcinoma patients

Characteristic

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Overall survival

 DNAH status

0.510 (0.276–0.0941)

0.031

0.457 (0.235–0.886)

0.021

 TNM stage

1.841 (1.081–3.147)

0.025

1.367 (0.794–2.353)

0.259

 R0 resection

4.699 (2.021–10.927)

<0.001

4.459 (1.689–11.773)

0.003

 Grade

1.170 (0.636–2.152)

0.614

  

 Age at diagnosis, y

1.014 (0.985–1.044)

0.343

  

Progression-free survival

 DNAH status

0.544 (0.291–1.016)

0.056

  

 TNM stage

0.952 (0.597–1.518)

0.873

  

 R0 resection

0.139 (0.746–8.157)

0.139

  

 Grade

2.303 (1.097–4.837)

0.028

2.303 (1.097–4.837)

0.028

 Age at diagnosis, y

0.996 (0.966–1.026)

0.773

  
  1. Statistically significant values are in italics