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Table 1 Univariate and multivariate models for overall survival and progression-free survival in 132 gastric cancer patients who underwent chemotherapy in The Cancer Genome Atlas (TCGA)

From: Somatic mutation of DNAH genes implicated higher chemotherapy response rate in gastric adenocarcinoma patients

Characteristic Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Overall survival
 DNAH status 0.510 (0.276–0.0941) 0.031 0.457 (0.235–0.886) 0.021
 TNM stage 1.841 (1.081–3.147) 0.025 1.367 (0.794–2.353) 0.259
 R0 resection 4.699 (2.021–10.927) <0.001 4.459 (1.689–11.773) 0.003
 Grade 1.170 (0.636–2.152) 0.614   
 Age at diagnosis, y 1.014 (0.985–1.044) 0.343   
Progression-free survival
 DNAH status 0.544 (0.291–1.016) 0.056   
 TNM stage 0.952 (0.597–1.518) 0.873   
 R0 resection 0.139 (0.746–8.157) 0.139   
 Grade 2.303 (1.097–4.837) 0.028 2.303 (1.097–4.837) 0.028
 Age at diagnosis, y 0.996 (0.966–1.026) 0.773   
  1. Statistically significant values are in italics
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Journal of Translational Medicine

ISSN: 1479-5876

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