Fig. 3

Changes in key parameters during observation period T0-T2 related to menopausal status. a Waist, b body fat, c LBD, d BMD, e LDL, f HDL, g triglycerides, h glucose, i insulin, j HOMA-IR, k HOMA-β, l SBP, m DBP, n Hs-CRP, o MetS. LBM lean body mass, BMD bone mineral density, LDL low-density lipoprotein, HDL high-density lipoprotein, HOMA-IR homeostatic model assessment of insulin resistance, HOMA β homeostatic model assessment of β-cell function, SBP systolic blood pressure, DBP diastolic blood pressure, Hs-CRP high sensitivity C-reactive protein, MetS metabolic syndrome. Dotted line, postmenopausal BC patients; straight line, premenopausal BC patients; grey-filled triangle, postmenopausal controls; black-filled triangle, premenopausal controls