Fig. 9
From: Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy
Dissolution kinetics of spray dried OZ439 NP powder after storage in an oven at 50 °C and 75% RH in uncapped vials. In all cases, NPs in FaSSIF achieved 80–90% maximum OZ439 solubilization, and NPs in FeSSIF reached 90–100% solubilization. Though there is more variability in the FeSSIF results (right), no trend of decreasing activity as a function of incubation time is observed