Fig. 2

Altered PGE2-EP2 expression in ACLF. a Representative plots for EP2 expression on CD8⁺ T cells from four groups. b EP2 expression on CD8⁺ T cells in HC (n = 36), CHB (n = 13) and ACLF (n = 34) was determined by flow cytometry. c Plasma PGE2 levels were measured in HC (n = 17), CHB (n = 17) and ACLF (n = 16) by ELISA. The horizontal line represented the median, and statistical analyses were performed using the Mann–Whitney test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, not statistically significant