Fig. 3

Exosomal miRNA expression in CRPS patients undergoing plasma exchange. A venn diagram showing relative expression of various miRNAs evaluated from serum exosomes of six CRPS patients before PE and 2 weeks following it. Comparison of miRNA levels are presented in responders (R) and poor responders (N) before (b) and after (a) PE. Upregulated miRNAs are shown in green and downregulated miRNAs in red, while miRNAs that are common between the compared groups but differing in directionality are in dark red. The significance was determined using student t-test (p < 0.05)