| |
Mean OS (95% CI)a (months)
|
p-value
|
|---|
|
Overall
|
9.2 (5.3–13.2)
| |
|
Age (years)
|
|
≤ 70
|
6.1 (0.3–11.8)
|
0.27
|
|
> 70
|
10.0 (7.2–12.8)
|
|
Gender
|
|
Male
|
8.9 (5.1–12.8)
|
0.76
|
|
Female
|
9.2 (2.3–16.1)
|
|
Histology
|
|
Adenocarcinoma
|
9.2 (4.6–13.9)
|
0.56
|
|
Squamous
|
9.8 (2.5–17.2)
|
|
PS ECOG
|
|
0
|
9.2 (5.6–12.8)
|
0.65
|
|
> 1
|
2.0 (0.1–5.4)
|
|
Smoke
|
|
Never smoker
|
9.9 (0.1–20.5)
|
0.80
|
|
Smoker
|
8.9 (4.7–13.2)
|
|
Prior treatment lines, n
|
|
1
|
6.1 (3.6–8.5)
|
0.036
|
|
≥ 2
|
12.2 (8.2–13.3)
|
|
RECIST response
|
|
No response
|
6.4 (4.8–8.0)
|
< 0.001
|
|
Response
|
13.5 (11.2–15.7)
|
- aMedian survival not reached
