Table 1 Clinical characteristics of patients for whom NICS was performed on embryo culture medium
From: Chromosome screening using culture medium of embryos fertilised in vitro: a pilot clinical study
|  | Chromosomal rearrangement (n = 23) | Normal karyotype (n = 22) | Entire cohort (n = 45) |
|---|---|---|---|
Female age (years) | 29.4 ± 5.4 | 31.7 ± 4.5 | 30.7 ± 5.0 |
Female body mass index (kg/m2) | 21.5 ± 3.1 | 23.0 ± 3.2 | 22.3 ± 3.2 |
Baseline FSH (mIU/mL) | 6.8 ± 2.5 | 6.8 ± 1.4 | 6.8 ± 2.1 |
Baseline LH (mIU/mL) | 5.0 ± 3.4 | 5.6 ± 2.4 | 5.4 ± 2.9 |
Infertility duration (years) | 3.0 ± 1.9 | 3.2 ± 2.7 | 3.1 ± 2.4 |
Number of cycles | 25 | 22 | 47 |
CCOCs | 345 | 292 | 637 |
MII | 285 | 216 | 501 |
Zygotes | 237 (83.2%) | 184 (85.2%) | 421 (84.0%) |
Embryos obtained | 234 (98.7%) | 179 (97.3%) | 413 (98.1%) |
Blastocysts obtained | 97 (41.5%) | 82 (45.8%) | 179 (43.3%) |
Blastocysts subjected to NICS | 95 | 75 | 170 |
 Euploid | 41 (43.2%) | 38 (50.7%) | 79 (46.5%) |
 Aneuploid | 31 (32.6%) | 21 (28.0%) | 52 (30.6%) |
 Mosaic | 17 (17.9%) | 16 (21.3%) | 33 (19.4%) |
 Unsuitable for implantation by NICS | 6 (6.3%) | 0 | 6 (3.5%) |
Cycles without transferable blastocysts | 4% (1/25) | 4.5% (1/22) | 4.3% (2/47) |