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Table 2 Geometrical features of Sirius red stained pancreatic collagenic ECM and simulated degradation

From: Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: a pilot study

  Computer-aided morphometric analysis Computer modeling
Cases ROI Sirius-red stained surface (%) Sirius-red stained collagenic ECM geometrical complexity (D) Erosion cycles (n) Erosion velocity
Natural pancreatic tissue 5 50 2.23 ± 0.28 1.36 ± 0.02 12.94 ± 0.94 0.15 ± 0.01
Pancreatitis 6 60 14.27 ± 1.27 1.70 ± 0.01 21.27 ± 1.43 0.67 ± 0.04
PDAC 7 70 22.30 ± 2.03 1.74 ± 0.01 27.61 ± 1.43 0.73 ± 0.04
  1. Data are expressed as mean ± standard deviation
  2. ROI region of interest, PDAC pancreatic adenocarcinoma