Table 2 Geometrical features of Sirius red stained pancreatic collagenic ECM and simulated degradation
Computer-aided morphometric analysis | Computer modeling | |||||
|---|---|---|---|---|---|---|
Cases | ROI | Sirius-red stained surface (%) | Sirius-red stained collagenic ECM geometrical complexity (D) | Erosion cycles (n) | Erosion velocity | |
Natural pancreatic tissue | 5 | 50 | 2.23 ± 0.28 | 1.36 ± 0.02 | 12.94 ± 0.94 | 0.15 ± 0.01 |
Pancreatitis | 6 | 60 | 14.27 ± 1.27 | 1.70 ± 0.01 | 21.27 ± 1.43 | 0.67 ± 0.04 |
PDAC | 7 | 70 | 22.30 ± 2.03 | 1.74 ± 0.01 | 27.61 ± 1.43 | 0.73 ± 0.04 |