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Table 2 Characteristics of patients in subgroups stratified by alterations of Th2/Th1

From: Early and dynamic alterations of Th2/Th1 in previously immunocompetent patients with community-acquired severe sepsis: a prospective observational study

Characteristic

Early recovery

(n = 35)

Late recovery

(n = 19)

Non-recovery

(n = 17)

p

Age, mean ± SD, years

72.0 ± 16.8

75.7 ± 11.4

67.5 ± 16.2

ns

Gender (male/female)

25/10

10/9

10/7

ns

Admission sources, n (%)

   

0.03

 Emergency

23 (65.7)

18 (94.7)

16 (94.1)

 

 Internal dept.

5 (14.3)

1 (5.3)

0

 

 Surgical dept.

7 (20)

0

2 (11.8)

 

APACHE II, mean ± SD

20.9 ± 5.3

19.5 ± 4.2

20.8 ± 8.0

 

SOFA, mean ± SD

    

 D0

9.3 ± 2.1

11.2 ± 3.1

9.6 ± 4.5

ns

 D3

6.3 ± 2.6

10.8 ± 3.3

8.2 ± 3.8

< 0.001

 D7

6.0 ± 3.2

8.0 ± 2.5

7.9 ± 4.0

ns

Presumed infection site, n (%)

   

ns

 Lung

22 (62.9)

17 (89.5)

11 (64.7)

 

 Abdomen

6 (17.1)

2 (10.5)

3 (17.6)

 

 Cardiovascular system

2 (5.7)

0

1 (5.9)

 

 Bone or soft tissue

0

0

1 (5.9)

 

 Urinary tract

5 (14.3)

0

1 (5.9)

 

Comorbidities, n (%)

 Hypertension

20 (57.1)

11 (57.8)

7 (41.2)

ns

 Diabetes

8 (22.9)

6 (31.6)

6 (35.3)

ns

 Chronic cardiac dysfunction

11 (31.4)

12 (63.2)

4 (23.5)

0.03

 Cerebrovascular disease

11 (31.4)

9 (47.4)

8 (47.1)

ns

 Chronic renal dysfunction

2 (5.7)

2 (10.5)

1 (5.9)

ns

Smoker

   

ns

 Never

23 (65.7)

13 (68.4)

11 (64.7)

 

 Previous (stopped > 3 months)

8 (22.9)

4 (21.1)

2 (11.8)

 

 Former (stopped ≤ 3 months)

0 (0)

0 (0)

0 (0)

 

 Current

4 (11.4)

2 (10.5)

4 (23.5)

 

Alcohol use

   

ns

 Never or daily intake ≤ 50 g of pure alcohol

31 (88.6)

18 (94.7)

15 (88.2)

 

 Previous (daily intake > 50 g of pure alcohol, stopped > 3 months)

2 (5.7)

1 (5.6)

0 (0)

 

 Former (daily intake > 50 g of pure alcohol, stopped ≤ 3 months)

0 (0)

0 (0)

0 (0)

 

 Current intake (> 50 g of pure alcohol)

2 (5.7)

0 (0)

2 (11.8)

 
  1. Chi square tests were used for categorical data, Student’s t-test for normally distributed continuous data and Mann–Whitney-U tests for nonnormally distributed data
  2. APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment