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Table 2 Characteristics of patients in subgroups stratified by alterations of Th2/Th1

From: Early and dynamic alterations of Th2/Th1 in previously immunocompetent patients with community-acquired severe sepsis: a prospective observational study

Characteristic Early recovery
(n = 35)
Late recovery
(n = 19)
Non-recovery
(n = 17)
p
Age, mean ± SD, years 72.0 ± 16.8 75.7 ± 11.4 67.5 ± 16.2 ns
Gender (male/female) 25/10 10/9 10/7 ns
Admission sources, n (%)     0.03
 Emergency 23 (65.7) 18 (94.7) 16 (94.1)  
 Internal dept. 5 (14.3) 1 (5.3) 0  
 Surgical dept. 7 (20) 0 2 (11.8)  
APACHE II, mean ± SD 20.9 ± 5.3 19.5 ± 4.2 20.8 ± 8.0  
SOFA, mean ± SD     
 D0 9.3 ± 2.1 11.2 ± 3.1 9.6 ± 4.5 ns
 D3 6.3 ± 2.6 10.8 ± 3.3 8.2 ± 3.8 < 0.001
 D7 6.0 ± 3.2 8.0 ± 2.5 7.9 ± 4.0 ns
Presumed infection site, n (%)     ns
 Lung 22 (62.9) 17 (89.5) 11 (64.7)  
 Abdomen 6 (17.1) 2 (10.5) 3 (17.6)  
 Cardiovascular system 2 (5.7) 0 1 (5.9)  
 Bone or soft tissue 0 0 1 (5.9)  
 Urinary tract 5 (14.3) 0 1 (5.9)  
Comorbidities, n (%)
 Hypertension 20 (57.1) 11 (57.8) 7 (41.2) ns
 Diabetes 8 (22.9) 6 (31.6) 6 (35.3) ns
 Chronic cardiac dysfunction 11 (31.4) 12 (63.2) 4 (23.5) 0.03
 Cerebrovascular disease 11 (31.4) 9 (47.4) 8 (47.1) ns
 Chronic renal dysfunction 2 (5.7) 2 (10.5) 1 (5.9) ns
Smoker     ns
 Never 23 (65.7) 13 (68.4) 11 (64.7)  
 Previous (stopped > 3 months) 8 (22.9) 4 (21.1) 2 (11.8)  
 Former (stopped ≤ 3 months) 0 (0) 0 (0) 0 (0)  
 Current 4 (11.4) 2 (10.5) 4 (23.5)  
Alcohol use     ns
 Never or daily intake ≤ 50 g of pure alcohol 31 (88.6) 18 (94.7) 15 (88.2)  
 Previous (daily intake > 50 g of pure alcohol, stopped > 3 months) 2 (5.7) 1 (5.6) 0 (0)  
 Former (daily intake > 50 g of pure alcohol, stopped ≤ 3 months) 0 (0) 0 (0) 0 (0)  
 Current intake (> 50 g of pure alcohol) 2 (5.7) 0 (0) 2 (11.8)  
  1. Chi square tests were used for categorical data, Student’s t-test for normally distributed continuous data and Mann–Whitney-U tests for nonnormally distributed data
  2. APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment