Fig. 4
From: RIPK1 inhibition attenuates experimental autoimmune arthritis via suppression of osteoclastogenesis
NST-1s represses IL-17 but maintains Foxp3 expression in CD4 + T cells in CIA mice. a, b Flow cytometric analysis shows the Th1 cells (CD4+ IFN-r+), Th2 cells (CD4+ IL-4+), Th17 cells (CD4+ IL17+) and Tregs (CD4+ CD25+ FOXP3+) in splenocytes of CIA mice. c Spleen tissues from each mice were stained for Th1, Th2, Th17 and Tregs were enumerated visually at higher magnification, and the mean values are presented in the form of histogram (right panel). *p < 0.05; **p < 0.01; ***p < 0.001