Skip to main content

Table 2 Distribution frequencies AIS osteopenia, AIS normal bone mass and control groups

From: Adiponectin regulates bone mass in AIS osteopenia via RANKL/OPG and IL6 pathway

Single nucleotide polymorphism (associate gene) Group A (AIS osteopenia) Group B (AIS normal bone mass) Group C (control) pA–B–C pA–B pA–C pB–C
Number (%) Number (%) Number (%)
rs7639352 (ADIPOQ)
 C/C 65 (32.5%) 95 (45.5%) 118 (57.3%) < 0.05 0.006 < 0.0167 0.032
 T/T 32 (16%) 17 (8.1%) 18 (8.7%)     
 C/T 103 (51.5%) 97 (46.4%) 70 (34%)     
Allele
 C 233 (58.25%) 287 (68.7%) 306 (74.3%) < 0.05 0.002 < 0.0167 0.074
 T 167 (41.75%) 131 (31.3%) 106 (25.7%)     
rs10937273 (ADIPOQ)
 G/G 72 (36%) 70 (33.5%) 72 (35%) 0.957    
 A/A 33 (16.5%) 33 (15.8%) 36 (17.5%)     
 G/A 95 (47.5%) 106 (50.7%) 98 (47.6%)     
rs1648707 (ADIPOQ)
 C/C 50 (25%) 42 (20.1%) 48 (23.3%) 0.588    
 A/A 51 (25.5%) 62 (29.7%) 64 (31.1%)     
 C/A 99 (49.5%) 105 (50.2%) 94 (45.6%)     
rs266719 (ADIPOQ)
 C/C 154 (77%) 167 (79.9%) 156 (75.7%) 0.355    
 T/T 3 (1.5%) 2 (1%) 0 (0%)     
 C/T 43 (21.5%) 40 (19.1%) 50 (24.3%)     
rs822354 (ADIPOQ)
 G/G 150 (75%) 150 (71.8%) 140 (68%) 0.585    
 A/A 3 (1.5%) 5 (2.4%) 4 (1.9%)     
 G/A 47 (23.5%) 54 (25.8%) 62 (30.1%)     
rs822387 (ADIPOQ)
 T/T 199 (99.5%) 208 (99.5%) 206 (100%) 0.603    
 C/T 1 (0.5%) 1 (0.5%) 0     
rs17300539 (ADIPOQ)
 G/G 200 (100%) 209 (100%) 206 (100%) 1    
rs12342 (ADIPOQ RECEPTOR 2)
 C/C 51 (25.5%) 45 (21.5%) 56 (27.2%) 0.236    
 T/T 43 (21.5%) 61 (29.2%) 58 (28.2%)     
 C/T 106 (53%) 103 (49.3%) 92 (44.7%)     
rs11642015 (FTO)
 C/C 156 (78%) 159 (76.1%) 150 (72.8%) 0.801    
 T/T 4 (2%) 4 (1.9%) 4 (1.9%)     
 C/T 40 (20%) 46 (22%) 52 (25.2%)     
  1. Chi square test was use to tested, when p value > 0.05, there was no significant difference in all the groups; when p value < 0.05, then using bonferroni correction to test each two groups. pA–B–C represents difference among three groups. pA-B represents difference between group A and B. pA–C represents difference between group A and C. pB–C represents difference between group B and C. If p value < 0.0167, there was significant difference between two groups. The italic values represent the significant difference
\