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Table 3 Associations between anthropometric measurements and risk of post-prandial hyperglycaemia in normoglycemic patients

From: Discriminatory ability of anthropometric measurements of central fat distribution for prediction of post-prandial hyperglycaemia in patients with normal fasting glucose: the DICAMANO Study

Anthropometric measurement Category P for trend
Low Intermediate High
Total body fat
 Body mass index, median (minimum, maximum) 27.7 (25.1, 29.9) 32.5 (30.0, 34.8) 39.7 (35.1, 80.1)  
  N 120 155 172  
  Cases of post-prandial hyperglycaemia (%) 17.5 25.8 30.8  
  OR (95% CI) 1.0 (reference) 1.6 (0.9–3.0) 2.1 (1.2–3.7) 0.014
  Age- and gender-adjusted OR (95% CI) 1.0 (reference) 1.4 (0.8–2.6) 2.0 (1.1–3.5) 0.023
  Multivariable-adjusted OR (95% CI)a 1.0 (reference) 1.4 (0.7–2.5) 2.0 (1.1–3.6) 0.018
 Body adiposity index, median (minimum, maximum) 29.8 (21.3, 33.3) 36.1 (33.4, 38.5) 42.8 (38.7, 74.0)  
  N 149 149 149  
  Cases of post-prandial hyperglycaemia (%) 28.9 20.1 27.5  
  OR (95% CI) 1.0 (reference) 0.6 (0.4–1.1) 0.9 (0.6–1.6) 0.816
  Age- and gender-adjusted OR (95% CI) 1.0 (reference) 0.9 (0.5–1.7) 1.5 (0.8–2.9) 0.155
  Multivariable-adjusted OR (95% CI)a 1.0 (reference) 0.9 (0.5–1.6) 1.5 (0.8–2.8) 0.95
Central fat distribution
 Neck circumference, median (minimum, maximum) 34 (30, 35) 38 (36, 40) 44 (41, 57)  
  N 153 156 138  
  Cases of post-prandial hyperglycaemia (%) 15.7 24.4 37.7  
  OR (95% CI) 1.0 (reference) 1.7 (0.9–3.1) 3.3 (1.9–5.7) <0.001
  Age- and gender-adjusted OR (95% CI) 1.0 (reference) 1.7 (0.9–3.1) 3.3 (1.4–7.7) 0.005
  Multivariable-adjusted OR (95% CI)a 1.0 (reference) 1.8 (1.0–3.3) 3.3 (1.4–7.7) <0.001
 Waist circumference, median (minimum, maximum) 93 (73, 100) 107 (101, 114) 124 (115, 170)  
  N 156 149 142  
  Cases of post-prandial hyperglycaemia (%) 14.7 28.2 34.5  
  OR (95% CI) 1.0 (reference) 2.3 (1.3–4.0) 3.1 (1.7–5.3) <0.001
  Age- and gender-adjusted OR (95% CI) 1.0 (reference) 1.9 (1.1–3.5) 2.3 (1.3–4.3) 0.010
  Multivariable-adjusted OR (95% CI)a 1.0 (reference) 2.0 (1.1–3.6) 2.4 (1.3–4.4) 0.010
 Waist-to-hip ratio, median (minimum, maximum) 0.83 (0.71, 0.88) 0.93 (0.89, 0.97) 1.04 (0.98, 1.30)  
  N 150 156 141  
  Cases of post-prandial hyperglycaemia (%) 17.3 18.6 41.8  
  OR (95% CI) 1.0 (reference) 1.1 (0.6–2.0) 3.4 (2.0–5.9) <0.001
  Age- and gender-adjusted OR (95% CI) 1.0 (reference) 0.9 (0.5–1.7) 2.4 (1.2–4.7) 0.010
  Multivariable-adjusted OR (95% CI)a 1.0 (reference) 0.9 (0.5–1.7) 2.3 (1.2–4.7) 0.011
 Waist-to-height ratio, median (minimum, maximum) 0.57 (0.47, 0.61) 0.65 (0.62, 0.68) 0.76 (0.69, 1.11)  
  N 167 145 135  
  Cases of post-prandial hyperglycaemia (%) 15.6 26.2 37.0  
  OR (95% CI) 1.0 (reference) 1.9 (1.1–3.4) 3.2 (1.9–5.5) <0.001
  Age- and gender-adjusted OR (95% CI) 1.0 (reference) 1.6 (0.9–2.9) 2.5 (1.4–4.4) 0.001
  Multivariable-adjusted OR (95% CI)a 1.0 (reference) 1.6 (0.9–2.9) 2.5 (1.4–4.5) 0.001
  1. Italic values refers to statistically significant difference as compared with the lowest tertile (reference category)
  2. CI confidence interval, OGTT oral glucose tolerance test
  3. aAdditionally, adjusted for fasting plasma glucose level, smoking, and physical activity