Body mass index (kg/m2) | Waist circumference (cm) | Waist-to-hip ratio | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Low (25.1–29.9) | Intermediate (30.0–34.9) | High (> 35) | p-value | Low (73–100) | Intermediate (101–114) | High (115–170) | p-value | Low (0.71–0.88) | Intermediate (0.89–0.97) | High (0.98–1.30) | p-value | |
N | 120 | 155 | 172 | 156 | 149 | 142 | 150 | 156 | 141 | |||
Age, years | 40 (14) | 42 (14) | 40 (13) | 0.229 | 38 (13) | 42 (14) | 43 (14) | 0.005 | 35 (12) | 41 (13) | 47 (13) | < 0.001 |
Gender, women, n (%) | 91 (76) | 100 (64) | 100 (58) | 0.008 | 132 (85) | 101 (68) | 58 (41) | < 0.001 | 142 (95) | 108 (69) | 41 (29) | < 0.001 |
Smoking, n (%) | 29 (24) | 40 (26) | 36 (21) | 0.571 | 41 (26) | 29 (19) | 35 (25) | 0.345 | 31 (21) | 42 (27) | 32 (23) | 0.419 |
Physical activity level, n (%) | ||||||||||||
Sedentary or light activity | 84 (70) | 118 (76) | 140 (81) | 0.050 | 115 (74) | 109 (73) | 118 (83) | 0.133 | 114 (76) | 112 (72) | 116 (82) | 0.229 |
Active or moderately active | 34 (28) | 37 (24) | 29 (17) | 39 (25) | 39 (26) | 22 (15) | 35 (23) | 41 (26) | 24 (17) | |||
Vigorous or vigorously active | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
Unknown | 2 (2) | 0 (0) | 3 (2) | 2 (1) | 1 (1) | 2 (1) | 1 (1) | 3 (2) | 2 (1) | |||
Fasting plasma glucose level, mmol l−1 | 5.1 (0.4) | 5.0 (0.3) | 5.1 (0.3) | 0.862 | 5.0 (0.4) | 5.0 (0.3) | 5.1 (0.3) | 0.408 | 4.9 (0.4) | 5.0 (0.3) | 5.1 (0.3) | < 0.001 |
Basal insulin, pmol l−1 | 56.9 (55.5) | 76.4 (76.4) | 97.2 (62.5) | < 0.001 | 62.5 (62.5) | 76.4 (69.4) | 104.2 (62.5) | < 0.001 | 69.4 (76.4) | 76.4 (55.5) | 97.2 (62.5) | < 0.001 |
HOMA-IR | 1.8 (1.6) | 2.4 (2.6) | 3.2 (2) | < 0.001 | 1.9 (2) | 2.5 (2.3) | 3.4 (2.1) | < 0.001 | 2.2 (2.7) | 2.3 (1.7) | 3.2 (2) | < 0.001 |
Insulin sensitivity index | 5.8 (3.6) | 4.9 (3) | 3.6 (2.8) | < 0.001 | 5.9 (3.6) | 4.5 (2.8) | 3.3 (2.6) | < 0.001 | 5.8 (3.6) | 4.8 (3.2) | 3.2 (2) | < 0.001 |
Disposition index | 6 (5.1) | 5.2 (4.6) | 4.3 (5.4) | < 0.022 | 6 (5) | 5.2 (6.2) | 3.9 (3.3) | 0.001 | 6.3 (6.6) | 5 (4.4) | 3.8 (3.1) | < 0.001 |
Quantitative insulin sensitivity check index | 0.36 (0.04) | 0.35 (0.04) | 0.33 (0.04) | 0.001 | 0.37 (0.04) | 0.35 (0.04) | 0.33 (0.04) | < 0.001 | 0.36 (0.05) | 0.35 (0.04) | 0.33 (0.04) | < 0.001 |
Insulinogenic index | 1.2 (1.6) | 1.2 (0.9) | 1.5 (1.6) | 0.092 | 1.2 (1.4) | 1.3 (1.5) | 1.5 (1.3) | 0.258 | 1.2 (1.7) | 1.3 (1.4) | 1.4 (1) | 0.712 |
Waist-to-height ratio | Neck circumference (cm) | |||||||
---|---|---|---|---|---|---|---|---|
Low (0.47–0.61) | Intermediate (0.62–0.68) | High (0.69–1.11) | p-value | Low (30–35) | Intermediate (36–40) | High (41–57) | p-value | |
N | 167 | 145 | 135 | 153 | 156 | 138 | ||
Age, years | 37 (12) | 42 (13) | 44 (14) | < 0.001 | 39 (13) | 40 (14) | 44 (13) | 0.004 |
Gender, women, n (%) | 120 (72) | 93 (64) | 78 (58) | 0.037 | 153 (100) | 121 (77) | 17 (12) | < 0.001 |
Smoking, n (%) | 39 (23) | 36 (25) | 30 (22) | 0.875 | 38 (25) | 31 (20) | 36 (26) | 0.405 |
Physical activity level, n (%) | ||||||||
Sedentary or light activity | 117 (70) | 110 (76) | 115 (85) | 0.013 | 100 (72) | 118 (75) | 114 (76) | 0.154 |
Active or moderately active | 48 (29) | 34 (23) | 18 (13) | 42 (27) | 35 (22) | 23 (17) | ||
Vigorous or vigorously active | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
Unknown | 2 (1) | 1 (1) | 2 (1) | 1 (1) | 3 (2) | 1 (1) | ||
Fasting plasma glucose level, mmol l−1 | 5.1 (0.3) | 4.9 (0.3) | 5.1 (0.3) | 0.015 | 4.9 (0.4) | 5.0 (0.3) | 4.6 (0.3) | 0.004 |
Basal insulin, pmol l−1 | 62.5 (62.5) | 83.3 (69.4) | 104.2 (62.5) | < 0.001 | 62.5 (76.4) | 69.4 (55.5) | 104.2 (55.5) | < 0.001 |
HOMA-IR | 1.9 (2.1) | 2.6 (2.2) | 3.3 (2.2) | < 0.001 | 2.1 (2.5) | 2.3 (1.9) | 3.4 (1.9) | < 0.001 |
Insulin sensitivity index | 5.9 (3.6) | 4.3 (2.6) | 3.5 (2.8) | < 0.001 | 6 (3.6) | 4.8 (3.1) | 3 (1.8) | < 0.001 |
Disposition index | 6.1 (5.3) | 5.1 (5.9) | 3.7 (3.3) | < 0.001 | 6.6 (6) | 4.7 (5.2) | 3.8 (3.1) | < 0.001 |
Quantitative insulin sensitivity check index | 037 (0.04) | 0.35 (0.04) | 0.34 (0.04) | < 0.001 | 0.37 (0.05) | 0.35 (0.04) | 0.33 (0.03) | < 0.001 |
Insulinogenic index | 1.2 (1.3) | 1.4 (1.6) | 1.4 (1.3) | 0.366 | 1.3 (1.5) | 1.2 (1.3) | 1.5 (1.3) | 0.134 |