Fig. 1

LRRK2 expression profiles in the peripheral immune cells. Whole blood was collected from SLE patients and healthy volunteer donors. The expression levels of LRRK2 in PBMCs (a), CD4⁺ T cells and B cells (b) from SLE patients and healthy donors were determined by RT-qPCR. c The expression levels of LRRK2 in resting CD19^lo B cells and CD19^hi B cells from three healthy donors were calculated based on transcriptome assay data [24]. *p < 0.05; ***p  <  0.001