Table 3 Quantitative real-time polymerase chain reaction (qPCR) and mRNA microarray analysis for selected mRNAs
From: MicroRNA-regulated pathways of flow-stimulated angiogenesis and vascular remodeling in vivo
mRNA | qPCR | miRNA microarray | ||||
|---|---|---|---|---|---|---|
Fold change | P-value | Regulation | Fold change | P-value | Regulation | |
POD 5 | ||||||
 HIF1A | 2.18 | 0.214 | Up | 1.97 | 0.0003 | Up |
 TLR6 | 4.00 | 0.071 | Up | 4.11 | 0.0003 | Up |
 VEGFA | 3.45 | 0.22 | Up | 4.41 | 0.0007 | Up |
 THBS3 | − 14.29 | 0.001 | Down | − 8.78 | 5.33 × 10−6 | Down |
 NDRG2 | − 33.33 | 0.002 | Down | − 21.00 | 0.0005 | Down |
POD 10 | ||||||
 HIF1A | 1.69 | 0.049 | Up | 1.59 | 0.0380 | Up |
 TLR6 | 2.72 | 0.061 | Up | 2.22 | 0.1089 | Up |
 VEGFA | 3.46 | 0.015 | Up | 3.12 | 0.0379 | Up |
 THBS3 | − 7.14 | 0.001 | Down | − 1.36 | 0.0050 | Down |
 NDRG2 | − 7.69 | 0.003 | Down | − 10.91 | 0.0157 | Down |
POD 15 | ||||||
 HIF1A | 1.19 | 0.288 | Up | 1.38 | 0.3585 | Up |
 TLR6 | 2.22 | 0.003 | Up | 2.46 | 0.0106 | Up |
 VEGFA | 2.32 | 0.066 | Up | 2.71 | 0.1847 | Up |
 THBS3 | − 11.11 | 0.001 | Down | − 1.57 | 0.0008 | Down |
 NDRG2 | − 11.11 | 0.003 | Down | − 8.48 | 0.0002 | Down |