From: MicroRNA-regulated pathways of flow-stimulated angiogenesis and vascular remodeling in vivo
miRNA | Gene symbol | Mean fold-change miRNA | Mean fold-change mRNA | GO term | Correlation | P-value | Weighted context++ score | Weighted context++ score percentile |
---|---|---|---|---|---|---|---|---|
mRNAs inducing angiogenesis | ||||||||
 POD 5 | ||||||||
  let-7c-5p | CXCR2 | − 4.30 | 10.92 | 0045766 | − 0.66 | 3.31 × 10−6 | − 0.193 | 79 |
  let-7b-5p | CXCR2 | − 3.23 | 10.92 | 0045766 | − 0.64 | 3.47 × 10−6 | − 0.157 | 74 |
  miR-27b-3p | CXCR2 | − 2.77 | 10.92 | 0045766 | − 0.6 | 1.50 × 10−5 | − 0.157 | 91 |
  miR-10b-5p | CXCR2 | − 3.76 | 10.92 | 0045766 | − 0.57 | 3.58 × 10−5 | − 0.414 | 98 |
  miR-27b-3p | IL1A | − 2.77 | 35.67 | 0045766 | − 0.59 | 1.82 × 10−5 | − 0.203 | 94 |
mRNAs inhibiting angiogenesis | ||||||||
 POD 5 | ||||||||
  miR-130b-3p | EPHA2 | 4.51 | − 3.18 | 0016525 | − 0.61 | 9.76 × 10−6 | − 0.069 | 73 |
  miR-223-3p | EPHA2 | 6.76 | − 3.18 | 0016525 | − 0.6 | 1.46 × 10−5 | − 0.134 | 86 |
  miR-223-3p | SYNJ2BP | 6.76 | − 2.74 | 1903671 | − 0.73 | 1.85 × 10−7 | − 0.013 | 37 |
  miR-19b-3p | SYNJ2BP | 3.63 | − 2.74 | 0016525 | − 0.58 | 2.96 × 10−5 | − 0.052 | 52 |
 POD 10 | ||||||||
  miR-19b-3p | SYNJ2BP | 2.06 | − 2.19 | 0016525 | − 0.58 | 2.96 × 10−5 | − 0.052 | 52 |
  miR-223-3p | SYNJ2BP | 3.95 | − 2.19 | 0016525 | − 0.73 | 1.85 × 10−7 | − 0.086 | 77 |
 POD 15 | ||||||||
  miR-511-3p | FOXC1 | 6.52 | − 6.39 | 0016525 | − 0.56 | 4.33 × 10−5 | − 0.038 | 62 |
  miR-223-3p | SYNJ2BP | 5.12 | − 1.99 | 0016525 | − 0.73 | 1.85 × 10−7 | − 0.086 | 77 |
  miR-449a-5p | SYNJ2BP | 1.75 | − 1.99 | 0016525 | − 0.64 | 5.74 × 10−7 | − 0.143 | 74 |