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Table 1 Analysis of differentially expressed genes and pathways

From: IL-23 and PSMA-targeted duo-CAR T cells in Prostate Cancer Eradication in a preclinical model

 Top enhanced Gene Ontogeny pathwayGene count
1Mitotic cell cycle process52
2Cell cycle59
3Mitotic nuclear division39
4Cell division22
5Regulation of cell cycle42
6DNA replication21
7Small GTPase mediated signal transduction29
8Intracellular signal transduction22
9Positive regulation of mitotic cell cycle13
10Cytokinesis10
11Response to cytokine12
 Top upregulated gene symbolFold change
1IL1310.1
2IL45.9
3IL53.5
4IL43.1
5EPAS12.9
6IFNG1.7
7CSF21.5
8PTGS21.5
9ARG21.5
10CCL31.5
 Top enhanced KEGG pathway descriptionGene count
1Cytokine‐cytokine receptor interaction14
2TNF signalling pathway8
3T cell receptor signalling pathway5
4Jak-STAT signalling pathway7
5Trancriptional misregulation4
6p53 signalling pathway6
7Cell cycle7
8Toll‐like receptor signaling pathway7
9Adipocytokine signaling pathway5
10Fc epsilon RI signaling pathway5