Fig. 2

Performance of the 106-CDS panel for the tumour mutation burden evaluation. a Linear regression analysis of the 106-CDS panel-score with the tumour mutation burden (TMB) of lung adenocarcinoma (LUAD) in TCGA database (training set). b Linear regression analysis of the 106-CDS panel-score with the recalculated TMB in TCGA after excluding the mutations in cancer-related genes and the recurrent CDSs occurring in more than 5% samples. c Linear regression analysis of the 106-CDS panel-score and the TMB in the Matthew dataset. d Linear regression analysis of the 106-CDS panel-score and the TMB in the Rizvi dataset. The gray lines are 95% confidence intervals of the 106-CDS panel for the TMB evaluation