Fig. 6

Effects of Gdf11 gene transfer on STZ-induced type 2 diabetic mice. a Experiment schedule; b the body weight of mice 4 weeks after GDF11 treatment; c non-fasting blood glucose level after gene transfer; d serum glucose level in GTT; e area under the curve of GTT; f blood insulin level at the end of experiment; g serum glucose level in ITT; h results of HOMA-IR analysis for insulin resistance. Each data point represents mean ± SEM (n = 5). *P < 0.05 comparing to mice injected with pLIVE-SEAP