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Table 1 Baseline patient characteristics and MR-proANP plasma concentrations

From: Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients

Parameter All patients Non-sepsis Sepsis
Number 217 73 144
Sex (male/female) 133/84 48/25 85/59
Age median (range) [years] 64 (18–90) 61 (18–85) 65 (20–90)
APACHE-II score median (range) 18 (2–43) 13.5 (2–33) 19 (4–43)
SOFA score median (range) 9 (0–19) 7.0 (0–17) 9.5 (2–19)
SAPS2 score median (range) 41 (0–73) 41.0 (13–72) 40.5 (0–73)
ICU days median (range) 7 (1–137) 6 (1–45) 9 (1–137)
Death during ICU n(%) 46 (21.2%) 9 (12.3%) 37 (25.7%)
Death overall (total) n(%) 86 (39.6%) 22 (30.1%) 64 (44.4%)
Mechanical ventilation n(%) 144 (66.4%) 46 (63%) 98 (67%)
Preexisting diabetes n(%) 65 (30.0%) 22 (30.1%) 43 (29.9%)
BMI median (range) [m2/kg] 26.0 (15.3–86.5) 25.7 (15.9–40.5) 26.0 (15.3–86.5)
WBC median (range) [×103/µl] 12.9 (0.1–208) 12.5 (1.8–29.6) 13.8 (0.1–208)
CRP median (range) [mg/dl] 103.0 (5–230) 17 (5–230) 163.5 (5–230)
IL-6 median (range) [pg/ml] 145.0 (2–28,000) 66.5 (1.5–5000) 240 (2–28,000)
Procalcitonin median (range) [pmol/l] 0.7 (0.03–207.5) 0.2 (0.03–100) 1.8 (0.03–207.5)
Creatinine median (range) [mg/dl] 1.3 (0.1–15) 1.0 (0.2–15) 1.6 (0.1–10.7)
INR median (range) 1.16 (0.92–13) 1.17 (0.95–6.73) 1.16 (0.92–13)
MR-proANP day 1 median (range) [pmol/l] 214.0 (2.1–3417.0) 147.2 (2.1–1625.0) 246.6 (7.8–3417.0)
  1. For quantitative variables, median and range (in parenthesis) are given