Table 1 Timeline of experimental procedures in series 1 and 2
pnd | Series I | Series II |
|---|---|---|
0 | Day of birth | |
6–11 | No treatment | VPA (150 mg/kg) |
12 | VPA (150Â mg/kg), adaptation in Xe/air-exposure chamber | |
13 | Xe/air inhalation followed by negative geotaxis test | |
17 | Xe/air inhalation followed by gait test | |
20 | Acclimation to Xe/air-exposure chamber | Â |
21 | Xe/air inhalation followed by open field test | |
25 | Xe/air inhalation followed by elevated plus maze | |
28 | Â | Xe/air inhalation followed by test for social novelty |
32 | Â | Xe/air inhalation followed by social play behavior test |
35 | Xe/air inhalation followed by forced swim test | |
40 | Elevated O-maze | Â |