Fig. 3

Ingenuity Pathway Analysis (IPA) of 532 genes differently expressed among early and late passage BMSCs. Unseparated BMSCs were analyzed by RNA sequencing. The transcriptome of early passage BMSCs, passages 4 and 6, was compared with the transcriptome of late passage BMSCs, passages 9 and 10, and 523 genes were found to be differentially expressed (adjusted p value < 0.01, log2 fold change > 1). The 532 genes were subjected to IPA analysis