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Table 2 Summary table of semi-quantification of kidney stainings in transplanted animals fed either a normal or a high-fat diet maintained for 3 months after surgery (M3)

From: Hypercholesterolemia-induced increase in plasma oxidized LDL abrogated pro angiogenic response in kidney grafts

 

Normal diet

High-fat diet

Renal HIF1a expression by field

 Positive tubules

5.40 ± 0.53

11.52 ± 0.58*

 Positive cells

5.00 ± 0.63

11.88 ± 1.00*

 Surface area (%)

6.00 ± 0.35

13.70 ± 0.91*

Renal VEGF-A expression by field positive vessels

6.98 ± 0.47

2.78 ± 0.32*

Renal TSP-1 expression by field

 Positive glomerulus parietal cell

2.54 ± 0.28

2.72 ± 0.35

 Positive glomerulus

1.73 ± 0.29

3.12 ± 0.28*

 Positive tubules

2.69 ± 0.47

9.03 ± 1.39*

 Interstitium staining (%)

4.00 ± 0.63

16.83 ± 0.70*

 Tubular atrophy (%)

6.35 ± 1.30

16.80 ± 0.74*

 Trichrome staining (%)

6.31 ± 0.78

16.81 ± 0.47*

  1. Values are mean ± SD
  2. * p < 0.05 vs. normal diet, n = 5 in each group
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Journal of Translational Medicine

ISSN: 1479-5876

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