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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

Fig. 1

DNA methylation changes during the first years of life. a Principal Component Analysis (PCA) for 783659 CpG sites across all samples in our study. The two PCs represented explain approximately 30% of the variance in methylation levels. b Stacked barplots indicating the total number of dmCpGs detected as either 0 → 5 or 5 → 10 changes (see Additional file 3: Table S1 for the detailed names and annotations of the dmCpGs). c Stacked barplots depicting the relative distribution of dmCpGs and of the array background according to their CpG island-related or gene location-related status. d Violin plots showing the distribution of genomic CpG density for the detected dmCpGs and array background

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