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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery

Fig. 1

Biopsy needle with integrated optical fibers. a In the initial phase the tissue is in contact with the fibers. b When the release button is pressed the cutting mechanism extends forward while the fibers retract. The tissue can now enter the biopsy cavity. c When pressing the release button further the outer stylet will extend forward, thereby cutting the tissue in the biopsy cavity from its surrounding. d Photograph of the biopsy needle with extended inner stylet, with the cutting mechanism protruded similar to situation b. e Example of an H&E stained slide of the biopsy specimen. The side of the specimen that was not in contact with the fibers (in this case the left side) is marked with red pathology ink directly after retrieving the biopsy specimen from the cavity

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