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Table 1 Summary of OS data

From: Immunotherapy Bridge 2018 and Melanoma Bridge 2018: meeting abstracts

  Median OS, months (95% CI) HR (95% CI)
IPI 10 mg/kg IPI 3 mg/kg IPI 10 mg/kg vs IPI 3 mg/kg
ITT population 15.7 (11.6, 17.8) 11.5 (9.9, 13.3) 0.84 (0.71, 0.99)
BRAF mutant 33.2 (19.4, 45.2) 19.7 (11.6, 25.3) 0.70 (0.48, 1.02)
BRAF wild-type 13.8 (10.2, 17.0) 11.2 (9.2, 13.8) 0.90 (0.73, 1.11)
M0/M1a/M1b 25.9 (22.2, 36.3) 18.7 (15.3, 23.0) 0.77 (0.58, 1.02)
M1c no brain metastases 10.8 (8.2, 16.0) 10.9 (8.3, 13.1) 0.92 (0.71, 1.17)
M1c with brain metastases 7.0 (4.0, 12.8) 5.7 (4.2, 7.0) 0.72 (0.50, 1.05)