|
Characteristics
|
Total (n = 105)
|
|---|
|
Age, years
|
31.69 ± 5.65
|
|
Male, n (%)
|
99 (94.3)
|
|
BMI, kg/(m2)
|
29.07 ± 20.14
|
|
Family history of premature CAD, n (%)
|
20 (19.0)
|
|
History of MI, n (%)
|
52 (49.5)
|
|
Currently smoking, n (%)
|
70 (66.7)
|
|
Alcohol drinker, n (%)
|
42 (40.0)
|
|
Hypertension, n (%)
|
46 (43.8)
|
|
DM, n (%)
|
17 (16.2)
|
|
Statin, n (%)
|
81 (77.1)
|
|
TG, mmol/L
|
1.80 ± 0.84
|
|
TC, mmol/L
|
6.62 ± 7.49
|
|
HDL-C, mmol/L
|
0.89 ± 0.26
|
|
LDL-C, mmol/L
|
5.77 ± 3.38
|
|
Lp(a), mg/dL
|
210.40 (65.75–496.06)
|
|
Xanthoma, n (%)
|
12 (11.4)
|
|
Mutations, n (%)
|
40 (38.1)
|
|
LDLR, n (%)
|
15 (14.3)
|
|
APOB, n (%)
|
7 (6.7)
|
|
PCSK9, n (%)
|
2 (1.9)
|
|
STAP1, n (%)
|
1 (1.0)
|
|
LDLR Homozygote, n (%)
|
4 (4.8)
|
|
Two mutations, n (%)
|
11 (10.5)
|
- Data are expressed as mean ± SD, or n (%). BMI body mass index, CAD coronary artery disease, MI myocardial infarction, DM diabetes mellitus, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Lp(a) lipoprotein (a), APOB apolipoprotein B, LDLR low-density lipoprotein receptor, PCSK9 proprotein convertase subtilisin/Kexin type 9, STAP1 signal-transducing adaptor protein 1
