Table 1 GCX flow and/or chemical treatment with rationale, where applicable
| Chemical stimulus | Rationale | |||
|---|---|---|---|---|
| Untreated | Hep III-treated | |||
| Flow stimulus | Static | Yes | Yes | To assess whether GCX controls baseline EC behavior (as opposed to flow-induced EC behavior) |
| Uniform | Yes | Yes | To assess whether EC behavior in UF only occurs due to endothelium coverage by the GCX | |
| Disturbed | Yes | |||
| Rationale | To assess GCX expression and EC behavior in response to both pro- and anti-atherosclerotic flow patterns | |||