Chemical stimulus | Rationale | |||
---|---|---|---|---|
Untreated | Hep III-treated | |||
Flow stimulus | Static | Yes | Yes | To assess whether GCX controls baseline EC behavior (as opposed to flow-induced EC behavior) |
Uniform | Yes | Yes | To assess whether EC behavior in UF only occurs due to endothelium coverage by the GCX | |
Disturbed | Yes | |||
Rationale | To assess GCX expression and EC behavior in response to both pro- and anti-atherosclerotic flow patterns |