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Table 1 Baseline characteristics

From: Real-world use of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers/β-blocks in Chinese patients before acute myocardial infarction occurs: patient characteristics and hospital follow-up

Characteristics Before PS match p value After PS match p value
AAβ (n = 872) NO-AAβ (n = 1833) AAβ (n = 226) NO-AAβ (n = 452)
Demographic
 Age (years) 68 (58–78) 63 (55–76) < 0.001 64 (55–77) 66 (55–78) 0.56
 Male sex 582 (66.7) 1336 (72.9) 0.001 155 (68.6) 319 (70.6) 0.60
 BMI (kg/m2) 25.6 (23.4–27.9) 25.0 (22.9–27.4) 0.001 25.4 (23.4–28.0) 25.3 (22.9–27.6) 0.28
Initial presentation
 SBP (mmHg) 133 (122–149) 126 (112–140) < 0.001 130 (117–144) 130 (118–144) 0.93
 DBP (mmHg) 74 (67–82) 72 (65–80) < 0.001 74 (67–83) 74 (65–82) 0.50
 Killip class ≥ 2 318 (36.5) 531 (29) < 0.001 65 (28.8) 130 (28.8) 0.23
Past history
 HT 836 (95.9) 940 (51.4) < 0.001 191 (84.5) 382 (84.5) 1
 DM 376 (43.1) 550 (30.0) < 0.001 29 (12.8) 67 (14.8) 0.48
 Dyslipidemia 414 (47.6) 689 (38.2) < 0.001 78 (34.5) 146 (32.3) 0.56
 Smoking 460 (52.8) 1144 (62.4) < 0.001 122 (54.0) 262 (58.2) 0.29
 CRF 96 (11) 101 (5.5) < 0.001 14 (6.19) 23 (5.09) 0.55
 HF 24 (2.78) 11 (0.61) < 0.001 2 (0.88) 2 (0.44) 0.48
 CAD 459 (52.7) 594 (32.7) < 0.001 35 (15.5) 71 (15.7) 0.94
 Previous MI 149 (17.1) 172 (9.5) < 0.001 22 (9.7) 35 (7.8) 0.38
 Previous PCI 219 (25.1) 194 (10.6) < 0.001 18 (8.0) 17 (3.8) 0.02
 Stroke 188 (21.6) 285 (15.6) < 0.001 41 (18.1) 81 (17.9) 0.94
Laboratory finding
 TC (mmol/L) 4.10 (3.44–4.78) 4.42 (3.77–5.08) < 0.001 4.27 (3.61–4.86) 4.42 (3.84–5.04) 0.01
 TG (mmol/L) 1.35 (0.99–1.97) 1.40 (1.0–1.97) 0.287 1.27 (0.99–1.87) 1.38 (0.99–1.96) 0.21
 LDL-C (mmol/L) 2.33 (1.83–2.80) 2.55 (2.07–3.06) < 0.001 2.41 (1.96–2.93) 2.60 (2.13–3.01) 0.004
 pNT-proBNP (ng/L) 2035 (587–7645) 1637 (557–5475) 0.01 1712 (674–5693) 1701 (587–5598) 0.91
 Scr (μmol/L) 88.3 (75.0–106.8) 83.5 (74.0–96.0) < 0.001 84.2 (74.4–101.6) 84.5 (75.0–95.7) 0.51
 GFR (mL/min 72.2 (55.2–87.3) 80.5 (64.1–95.1) < 0.001 74.7 (59.8–89.3) 78.1 (63.6–93.9) 0.14
Hospital course
 STEMI 326 (37.4) 980 (53.5) < 0.001 113 (50) 258 (57.1) 0.08
 NSTEMI 546 (62.6) 853 (46.5) < 0.001 113 (50) 194 (42.9) 0.08
 E-PCI 191 (29.7) 534 (36.5) 0.003 53 (29.0) 139 (37.6) 0.046
  1. AAβ ACEI/ARB/β-B, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HT hypertension, DM diabetes mellitus, CRF chronic renal failure, HF heart failure, CAD coronary artery disease, MI myocardial infarction, PCI percutaneous coronary intervention, TC total cholesterol, TG triglyceride, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, NT-proBNP N-terminal pro-brain natriuretic peptide, GFR glomerular filtration rate, STEMI ST-segment elevation AMI, NSTEMI non-ST-segment elevation AMI, E-PCI emergency percutaneous coronary intervention
  2. p values for comparisons between the two groups. Significance level was 0.05