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Table 4 Association of circadian pathway genes with predisposition to liposarcoma and leiomyosarcoma in subgroups analysis under the additive genetic model

From: Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis

Gene SNP ID Liposarcoma Leiomyosarcoma
OR [95% CI] P-val. OR [95% CI] P-val.
CLOCK rs1801260 0.67 [0.46–0.98] 0.04 0.84 [0.561.25] 0.39
  rs3736544 1.23 [0.881.71] 0.22 1.09 [0.761.57] 0.64
  rs3749474 1.09 [0.781.53] 0.60 1.00 [0.691.46] 0.98
NPAS2 rs895520 1.26 [0.901.75] 0.18 1.44 [0.99–2.09] 0.05
  rs2305160 1.01 [0.721.43] 0.95 0.88 [0.591.32] 0.54
PER1 rs3027178 0.68 [0.47–0.98] 0.04 0.96 [0.661.41] 0.85
PER2 rs934945 0.59 [0.37–0.96] 0.03 0.71 [0.421.20] 0.20
  rs7602358 1.23 [0.851.77] 0.28 1.16 [0.771.75] 0.49
RORA rs339972 0.75 [0.521.07] 0.12 0.64 [0.42–0.98] 0.04
  rs10519097 0.82 [0.511.31] 0.40 1.28 [0.802.06] 0.31
TIMELESS rs774027 0.98 [0.711.35] 0.90 0.95 [0.661.35] 0.76
  rs3809125 0.99 [0.711.38] 0.95 0.79 [0.531.16] 0.23
  rs7302060 1.00 [0.721.37] 0.97 1.01 [0.701.45] 0.97
  1. Italic values indicate statistically significant associations (P < 0.05)
  2. OR [95% CI] Odds Ratio [95% Confidence Interval], P-val. P-value