Fig. 4

Protein level validation using immunohistochemistry (IHC). PON1 protein expression in adjacent non-tumor tissues and tumor tissues. a PON1 location in HCC was demonstrated, particularly in the cytoplasm. Low and high expression in tumor tissues was also illustrated. The junction area is shown as a comparison. b Disease-free survival based on the IHC of 67 patients using the KM method (P = 0.14). c OS based on the IHC of 67 patients using the KM method (P = 0.043)