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Table 2 Incidence and Hazard ratio for depression and depression-associated risk factor

From: Scrub typhus and depression: a nationwide cohort analysis

Variable Event Person-years Ratea Crude HR (95% CI) Adjusted HRb (95% CI)
Scrub typhus
 No 117 108,433 1.08 1.00 1.00
 Yes 45 26,905 1.67 1.55 (1.41, 1.70)* 1.56 (1.42, 1.71)*
Sex
 Female 72 46,692 1.54 1.52 (1.39, 1.65)* 1.35 (1.24, 1.47)*
 Male 90 88,645 1.02 1.00 1.00
Age, year
 ≤ 49 77 81,148 0.95 1.00 1.00
 50–64 50 35,400 1.41 1.49 (1.35, 1.64)* 1.10 (0.99, 1.22)
 65 + 35 18,789 1.86 1.96 (1.76, 2.19)* 1.26 (1.11, 1.42)*
Diabetes
 No 133 124,334 1.07 1.00 1.00
 Yes 29 11,003 2.64 2.46 (2.21, 2.75)* 1.53 (1.35, 1.73)*
Hypertension
 No 125 120,702 1.04 1.00 1.00
 Yes 37 14,636 2.53 2.44 (2.21, 2.70)* 1.41 (1.24, 1.59)*
Hyperlipidemia
 No 141 129,514 1.09 1.00 1.00
 Yes 21 5823 3.61 3.31 (2.92, 3.76)* 2.08 (1.81,2 .40)*
CAD
 No 144 130,203 1.11 1.00 1.00
 Yes 18 5133 3.51 3.17 (2.77, 3.63)* 1.51 (1.29, 1.76)*
Stroke
 No 150 131,863 1.14 1.00 1.00
 Yes 12 3474 3.45 3.04 (2.58, 3.57)* 1.52 (1.27, 1.81)*
  1. aIncidence rate, per 1000 person-years; Crude HR, relative hazard ratio
  2. bMultivariable analysis including age, sex, and comorbidities of diabetes, hypertension, hyperlipidemia, CAD and stroke
  3. * P < 0.05