Fig. 3
From: Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis
The effects of SIM on alveolar bone loss and osteoid area. a ROI and representative images for the measurement of alveolar bone loss (H&E staining). The CEJ-ABC distance in the distal area (upper panels, black arrow) and the alveolar bone area (pale blue color) in the ROI (black line) of the furcation (lower panels) were measured in each rat. b The measurement of the CEJ-ABC distance in the distal area of each group. c Alveolar bone area as a percent of the ROI in the furcation of each group. d Osteoid area in the furcation of each group. Data are presented as the mean ± SE. Scale bar = 100 μm. *P < 0.05 compared with the C group. (C, n = 6; day 3: DP, n = 6 and DPS, n = 7; day 10: DP, n = 4 and DPS, n = 4; day 20: DP, n = 7 and DPS, n = 9)