Table 4 Univariate and multivariate analyses with respect to post-recurrence survival in breast cancer subtypes

All breast cancer (n = 55)

 Age (≤ 56)

0.639

0.301–1.331

0.231

0.369

0.076–1.337

 Menopause (−)

0.651

0.289–1.380

0.268

1.936

0.518–9.476

 Tumor size (> 2)

2.262

0.666–14.138

0.216

5.534

1.251–39.387

 Lymph node (+)

0.760

0.288–2.611

0.627

0.295

0.083–1.207

 Nuclear grade (3)

1.308

0.516–2.921

0.547

0.751

0.256–2.016

 Ki67 (> 14)

1.797

0.859–3.881

0.120

2.606

1.028–6.780

 Pathological response (non-pCR)

3.321

1.264–11.437

0.013

4.355

1.438–16.871

 Metastasis site (distant)

1.415

0.666–2.950

0.359

2.496

1.007–6.126

 Relapse-free survival (< 2 years)

2.439

1.005–7.269

0.049

1.938

0.681–6.598

Luminal (n = 23)

 Age (≤ 56)

1.228

0.382–3.948

0.724

5.415

0.194–115.713

 Menopause (−)

1.252

0.369–3.941

0.704

1.614

0.104–46.371

 Tumor size (> 2)

6.235 × 10⁷

0.822–0.822

0.073

3.108 × 10⁹

1.662–7.5 × 10¹⁷⁹

 Lymph node (+)

5.733 × 10⁷

0.561–0.561

0.135

1.772 × 10¹⁰

1.806–unparsable

 Nuclear grade (3)

1.198

0.265–4.042

0.791

0.436

0.034–4.914

 Ki67 (> 14)

1.118

0.345–3.648

0.849

0.982

0.180–4.386

 Pathological response (non-pCR)

7.144

1.358–131.592

0.016

300.204

7.824–52,372.311

 Metastatic site (distant)

2.520

0.740–7.971

0.132

15.037

2.182–159.623

 Relapse-free survival (< 2 years)

2.175

0.647–9.825

0.219

0.165

0.012–2.177

TNBC (n = 20)

 Age (≤ 56)

0.936

0.291–3.018

0.910

0.578

0.011–20.101

 Menopause (−)

1.025

0.299–3.258

0.967

0.919

0.022–36.398

 Tumor size (> 2)

0.948

0.222–6.663

0.949

2.141

0.100–93.753

 Lymph node (+)

0.507

0.133–2.415

0.360

1.083

0.049–53.468

 Nuclear grade (3)

1.841

0.479–6.155

0.350

0.109

0.003–1.421

 Ki67 (> 14)

4.242

1.078–28.056

0.038

51.171

1.769–4346.194

 Pathological response (non-pCR)

2.110

0.547–13.871

0.303

1.813

0.045–56.645

 Metastatic site (distant)

1.569

0.486–5.070

0.442

13.318

1.021–540.473

 Relapse-free survival (< 2 years)

7.070 × 10⁷

0.812–0.812

0.074

2.294 × 10⁷

0.027–3.0 × 10²⁸⁹