Table 3 Hub genes identified in the PPI interaction
Upregulated miRNAs | Downregulated miRNAs | ||
|---|---|---|---|
Gene symbol | Degree | Gene symbol | Degree |
TP53 | 80 | MYC | 42 |
AKT1 | 72 | AKT1 | 39 |
MAPK1 | 61 | VEGFA | 38 |
MYC | 51 | MAPK8 | 35 |
BCL2 | 46 | PIK3CG | 35 |
HRAS | 46 | BCL2 | 28 |
PTEN | 46 | FGF2 | 22 |
CALM3 | 45 | KRAS | 22 |
CDKN1A | 44 | PIK3R1 | 21 |
CYCS | 40 | SIRT1 | 21 |