Subtype-specific associations between breast cancer risk polymorphisms and the survival of early-stage breast cancer

Fu, Fangmeng; Guo, Wenhui; Lin, Yuxiang; Zeng, Bangwei; Qiu, Wei; Huang, Meng; Wang, Chuan

doi:10.1186/s12967-018-1634-0

Table 2 Genotyping results with EBC’s survival

From: Subtype-specific associations between breast cancer risk polymorphisms and the survival of early-stage breast cancer

SNPs	Cases WH/H/VH	iDFS (LogRank P)				DDFS (LogRank P)				BCSS (logRank P)				OS (Log Rank P)
SNPs	Cases WH/H/VH	Events WH/H/VH	DOM	REC	COD	Events WH/H/VH	DOM	REC	COD	Events WH/H/VH	DOM	REC	COD	Events WH/H/VH	DOM	REC	COD
rs10069690	789/353/34	298/139/8	0.938	0.065	0.152	273/129/8	0.689	0.128	0.221	218/107/7	0.510	0.230	0.291	225/110/7	0.533	0.191	0.257
rs13281615	293/575/308	126/196/124	0.043	0.397	0.035	112/186/112	0.178	0.619	0.241	86/154/93	0.592	0.402	0.482	89/157/97	0.531	0.320	0.362
rs13387042	932/234/11	351/91/4	0.803	1.000	0.968	322/84/4	0.767	0.830	0.944	264/66/3	0.891	0.891	0.977	274/66/3	0.664	0.934	0.898
rs1562430	801/344/32	297/136/13	0.419	0.787	0.720	272/125/13	0.363	0.516	0.600	228/97/8	0.840	0.738	0.938	234/100/9	0.940	0.955	0.996
rs2046210	361/602/214	142/220/84	0.327	0.873	0.611	134/198/78	0.180	0.964	0.361	107/162/64	0.359	0.970	0.633	112/166/65	0.231	0.829	0.481
rs2180341	715/394/68	270/147/29	0.858	0.381	0.679	245/136/29	0.556	0.136	0.326	198/115/20	0.554	0.783	0.836	204/118/21	0.547	0.676	0.809
rs2981582	493/545/139	187/204/55	0.891	0.459	0.708	173/189/48	0.843	0.843	0.945	143/149/41	0.491	0.554	0.556	146/154/43	0.581	0.459	0.547
rs3112612	776/354/46	290/140/15	0.541	0.563	0.610	263/132/14	0.263	0.660	0.391	210/110/12	0.213	0.818	0.393	218/111/13	0.290	1.000	0.545
rs3803662	532/512/133	214/185/47	0.102	0.472	0.258	193/172/45	0.309	0.795	0.594	157/138/38	0.284	0.957	0.537	165/139/39	0.141	0.946	0.309
rs4415084	392/558/226	144/204/98	0.332	0.043	0.124	130/189/91	0.256	0.038	0.106	105/152/76	0.245	0.039	0.107	110/156/77	0.345	0.059	0.160
rs4784227	550/513/113	191/211/44	0.035	0.714	0.104	177/195/38	0.077	0.905	0.164	146/155/32	0.173	0.793	0.389	148/162/33	0.091	0.773	0.235
rs889312	346/631/200	130/252/64	0.770	0.059	0.111	124/235/51	0.823	0.003	0.010	98/189/46	0.840	0.070	0.142	101/196/46	0.841	0.038	0.080
rs9485372	388/588/200	136/227/82	0.122	0.177	0.200	127/208/74	0.230	0.360	0.415	104/169/59	0.334	0.529	0.592	107/173/62	0.320	0.382	0.513
rs10474352	374/572/230	158/214/74	0.052	0.029	0.041	143/199/68	0.142	0.049	0.101	115/161/57	0.285	0.156	0.301	119/165/59	0.241	0.160	0.284
rs10816625	350/595/231	145/213/88	0.047	0.825	0.127	136/196/78	0.022	0.468	0.073	114/156/63	0.017	0.559	0.056	118/160/65	0.012	0.567	0.041
rs12922061	539/529/108	199/206/41	0.590	0.905	0.865	185/188/37	0.799	0.926	0.953	156/147/30	0.613	0.943	0.877	158/154/31	0.847	0.970	0.981
rs2290203	270/587/319	96/229/121	0.464	0.891	0.760	89/211/110	0.519	0.962	0.800	67/174/92	0.218	0.689	0.468	69/179/95	0.206	0.647	0.449
rs2296067	418/567/191	160/215/71	0.869	0.814	0.968	144/200/66	0.774	0.923	0.940	116/166/51	0.649	0.751	0.798	119/172/52	0.590	0.668	0.704
rs2981578	416/548/212	150/219/77	0.465	0.619	0.556	132/208/70	0.148	0.512	0.650	105/172/56	0.158	0.488	0.166	110/176/57	0.232	0.421	0.210
rs4951011	522/528/126	204/191/51	0.350	0.421	0.340	186/178/46	0.516	0.475	0.516	150/142/41	0.597	0.163	0.233	157/145/41	0.388	0.246	0.230
rs9693444	572/486/118	215/179/52	0.762	0.154	0.357	196/164/50	0.619	0.068	0.188	156/141/36	0.379	0.483	0.616	160/144/39	0.329	0.259	0.428

WH/H/VH wide homozygous type/heterozygote/variant homozygous type, DOM dominant model, REC recessive model, COD codominant model

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ISSN: 1479-5876

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