Table 1 Frequency of ABCB1 gene expression in patients metformin non user and metformin user
Metformin non-user, n = 76 (75%) | Metformin user, n = 26 (25%) | |
|---|---|---|
Age (median) | 35 (18–78) | 31 (18–61) |
Gender | ||
Male | 36 (47.4) | 13 (50) |
Female | 40 (52.6) | 13 (50) |
Leukocytes (median) (103/mcl) | 45.1 (0.4–251) | 42.1 (1.2–220) |
Type of risk | ||
Standard risk | 33 (43.4) | 18 (69.2) |
High risk | 43 (56.6) | 08 (30.8) |
Expression ABCB1 (%) | ||
Absence expression | 28 (36.8) | 8 (30.8) |
Low expression | 14 (18.4) | 6 (23.1) |
High expression | 34 (44.7) | 12 (46.2) |
Expression combination (%) | ||
Low and missing expression | 42 (55.3) | 14 (53.8) |
High expression | 34 (44.7) | 12 (46.2) |
Treatment failure | ||
Remission complete | 47 (61.8) | 18 (69.2) |
Death or refractoriness | 29 (38.2) | 08 (30.8) |